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Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease

Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06283043
Enrollment
54
Registered
2024-02-28
Start date
2024-01-01
Completion date
2024-03-05
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Impaired, Movement Disorders, Functional, Movement Disorders (Incl Parkinsonism), Parkinsonian Disorders

Keywords

Parkinson, Attention, motor function, sleep

Brief summary

Our study was planned to analyze motor function, endurance and sleep attention information in Parkinson's patients with detailed and objective measurements.

Detailed description

Parkinson's Disease (PD) is a neurodegenerative disease that occurs with the loss of dopaminergic neurons in the basal ganglia (BG) and subsequently affects multiple brain regions. There are studies that evaluate executive functions rather than cognitive functions in Parkinson's patients. However, objective evaluations of the attention parameter are quite rare. Accordingly, our study was planned to examine the effects of motor function, depression and sleep on attention in Parkinson's patients with detailed and objective measurements. Parkinson's patients (n=27) and healthy controls (n=27) aged between 40-85 will be included in the study. Balance evaluation of the individuals participating in the study was carried out by functional reaching test, one-leg standing test and Berg balance scale; Endurance with a 30-second sit-and-stand test; reaction time; with mobile application; muscle strength by hand dynamometer; functional mobility with time up and go test; walking speed, with 10 m walk test; attention with the P300 device; depression, with the Beck depression scale; Sleep quality will be assessed with the Pittsburg sleep questionnaire. At the end of the study, the effects of motor functions, sleep and depression on attention will be examined and compared with healthy controls.

Interventions

None listed

Sponsors

Inonu University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
40 Years to 80 Years

Inclusion criteria

* Being 1,2 or 3 according to the Hoehn and yahr scale * Being between the ages of 40-85 * Being diagnosed with Parkinson's according to UPDS * Being able to read and write * Being able to walk independently * Agreeing to participate in the study after providing detailed information about the research. * Mini mental test\>24

Exclusion criteria

* Having severe hearing/visual impairment-loss * Having an orthopedic, neurological or metabolic disease that may interfere with working * Having deep brain stimulation applied * Those with advanced cognitive impairment * Individuals with dementia * Patients taking anticholinergic, antidepressive or anxiolytic medications that may affect cognition, and those with other medical or neurological causes that may cause cognitive effects.

Design outcomes

Primary

MeasureTime frameDescription
TUGsecond, day 1, Values over 12 seconds indicate the risk of fallingfunctional mobility
10 m walking testsecond, day 1, lower results indicate better values, higher results indicate worse resultswalking speed
30 sec sit-stand testagain,day 1, higher results indicate better values, lower results indicate worse resultsendurance
berg balance testscore, day 1, The score is between 0-56. A high total score indicates a good resultbalance
one leg stance testsecond, day 1, higher results indicate better values, lower results indicate worse resultsbalance
functional reach testcentimeter, day 1, higher results indicate better values, lower results indicate worse resultsbalance
hand dinamometerkilogram, day 1, higher results indicate better values, lower results indicate worse resultsstrenght
mobil applicationsecond, day 1, lower results indicate better values, higher results indicate worse resultsreaction time
Pittsburg Sleep Quality İndexscore, day 1, The score is between 0-21. A high total score indicates a bad result.sleep
Beck Depressionscore,day 1, The total score is between 0-63. A high total score indicates that the result is bad.depression
P300second, day 1, lower results indicate better values, higher results indicate worse resultsattention

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026