Gastric Cancer, Gastric Xanthoma, Helicobacter Pylori Infection, Intestinal Metaplasia, Precancerous Lesions
Conditions
Keywords
gastric cancer, helicobacter pylori, precancerous lesion, Gastric Xanthoma
Brief summary
To explore the effects of gastric xanthoma on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
Detailed description
This is a large-scale single center case-control study. Patients were consecutively enrolled and divided into gastric cancer group, gastric precancerous lesions group, and chronic gastritis group, according to histopathological results.Record the location and quantity of gastric xanthoma and situation of Helicobacter pylori infection in each patient.
Interventions
None listed
Sponsors
Xijing Hospital of Digestive Diseases
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
1. Age range from 18 to 75 years old, regardless of gender; 2. Endoscopic/pathological diagnosis: chronic non atrophic gastritis/chronic atrophic gastritis/intestinal metaplasia/dysplasia Hyperplasia/gastric cancer 3. Voluntarily sign an informed consent form.
Exclusion criteria
1. Previously underwent upper gastrointestinal surgery 2. Previous diagnosis of malignant tumors 3. Individuals who are unable to cooperate with the questionnaire survey due to mental disorders or other reasons 4. Those who cannot be observed by endoscopy due to acute upper gastrointestinal bleeding or other reasons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| corelation between the gastric xanthoma and gastric mucosa diseases | up to 6 months | we evaluate the corelation between the gastric xanthoma and gastric mucosa diseases according to the histopathological results and the scales the patients finished |
Countries
China
Outcome results
None listed