Early Versus Conventional Loading for Fully Guided Immediate Implant Placement

Early Versus Conventional Loading for Fully Guided Immediate Implant Placement in Molar Sites (A Randomized Controlled Clinical Study)

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06281535

Enrollment

Registered

2024-02-28

Start date

2024-02-20

Completion date

2024-06-15

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implant

Keywords

early loading, conventional loading

Brief summary

Conventional loading protocol following implant placement 3 -6 months is considered the gold standard. However, early loading following 2 months after implant placement decreases the time and had a good survival rate.

Detailed description

The conventional loading protocol presented involves healing period of 3 -6 months. A healing period without stress was recommended in the order to present better survival rate. This loading protocol was developed in the time when micro- and macro design of implant surface was machine produced. Early loading of dental implants within 2 months following placement on healed posterior mandible showed 100% survival rate for five years follow up, with uneventful crestal bone loss. The lack of difference between conventional loading 6 months following implant placement and early loading could be explained by the fact that even if the crowns were not put in direct occlusion, patients used them functionally when chewing. The most relevant factor which may explain the positive results obtained in this trial is the high insertion torque at implant placement.

Interventions

DEVICEImplant loading

Placement of abutments and final restorations either 2 months following implant placement in early loading group or 3 months in conventional loading group

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Patients age range from 20-60 years. * Molar tooth to be extracted due to periodontal diseases, peri- apical diseases, Endo-perio diseases, or tooth fracture. * Primary implant stability is above 30 Ncm.

Exclusion criteria

* History or presence of severe uncontrolled systemic disease. * Heavy smokers (\>10 cigarettes per day) or alcohol/drug abusers. * Poor oral hygiene. * Acute periapical infection.

Design outcomes

Primary

Measure	Time frame	Description
Implant stability	2 and 3 months following implant placement	Degree of implant stability will be measured by Osstell device as a scale from 1 to 100

Contacts

Primary ContactDoaa Adel-Khattab, PhD

dr.doaa.adel-khattab@dent.asu.edu.eg01006814258

Backup ContactAbdel Rahman Khalaf, PHD

abdodent84@yahoo.com0116589954

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026