Acute Myocardial Infarction, Cancer
Conditions
Keywords
Acute myocardial infarction, Cancer, Incidence, Prognosis
Brief summary
Using national health insurance service database, current study aim to evaluate the risk and prognosis of acute myocardial infarction in cancer patients and to find the optimal treatment strategy for acute myocardial infarction that can improve long-term prognosis.
Detailed description
This study will be conducted using Korean National Health Insurance Service database. Patients who were diagnosed with cancer from 2002 to 2021 will be included in the study. Using the selected patients, current study will analyze the incidence and prognosis of acute myocardial infarction in cancer patients and the prognosis according to the treatment method for acute myocardial infarction will be compared. Primary outcome will be all-cause death. Secondary outcomes will be myocardial infarction, revascularization, hospitalization for heart failure, stroke, and clinically relevant bleeding.
Interventions
PROCEDURERevascularization
Performing PCI or CABG
Sponsors
Chonnam National University
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with cancer between 2002 and 2021 * Patients who were diagnosed with acute myocardial infarction after cancer diagnosis
Exclusion criteria
* Patients who died during period of cancer diagnosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause death | 2-years after diagnosis of acute myocardial infarction | All-cause death which was obtained from death certification collected by Statistics Korea at the Ministry of Strategy and Finance of South Korea |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Myocardial infarction | 2-years after diagnosis of acute myocardial infarction | Myocardial infarction is defined as presence of the diagnostic codes (ICD-10 I21, I22) in the primary position during hospitalization |
| Revascularization | 2-years after diagnosis of acute myocardial infarction | Percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) |
| Hospitalization for heart failure | 2-years after diagnosis of acute myocardial infarction | Heart failure events requiring hospitalization defined as presence of the diagnostic codes (I110, I130, I132, I255, I420, I425-I429, I43, I50, I971) in the primary position during hospitalization |
| Stroke | 2-years after diagnosis of acute myocardial infarction | Stroke is defined as ischemic stroke (ICD-10 I63, I64) or intracranial hemorrhage (ICD-10 I60-62), combined with the codes of diagnostic brain imaging. |
| Clinically relevant bleeding | 2-years after diagnosis of acute myocardial infarction | Bleeding requiring hospitalization or transfusion |
Countries
South Korea
Outcome results
None listed