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Perioperative Factors and Early Postoperative Kidney Graft Function Recovery

Analysis of Perioperative Factors Affecting Early Postoperative Kidney Graft Function Recovery in Patients Undergoing Living Kidney Transplant Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06280898
Enrollment
539
Registered
2024-02-28
Start date
2020-05-01
Completion date
2022-03-14
Last updated
2024-02-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Injuries, Kidney Transplant; Complications

Brief summary

Divided into two groups based on acute kidney injury: non-acute kidney injury group vs. non-acute kidney injury group. Acute kidney injury group, Acute Kidney Injury Network (AKIN), Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease (RIFLE), or Kidney Disease: Improving Global Outcomes (KDIGO) I would like to divide it according to the definition. After testing the normal distribution of patients, donors, grafts, types of immunosuppressants, surgery/anesthesia factors, and blood test findings between the two groups through the Shapiro-Wilk test, continuous data was tested using the student t-test or Mann-Whitney U test. Sizes are compared using , and categorical data is compared with proportions using the χ2 test or Fisher's exact test. Analysis of factors related to acute kidney injury will be performed through univariate and multivariate logistic regression analysis.

Interventions

PROCEDURERemote ischemic conditioning

Remote ischemic condition

Sponsors

Seoul St. Mary's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
19 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Adult patients aged 19 years or older who underwent kidney transplant surgery in the operating room

Exclusion criteria

* Pediatric patients under 19 years of age * Patients with multiple organ transplants, including kidney transplants * Patients undergoing re-kidney transplant surgery * Patient examination findings missing from electronic medical record

Design outcomes

Primary

MeasureTime frameDescription
Troponin Iup to 24 hour postoperativelyTroponin I difference in two groups

Secondary

MeasureTime frameDescription
Troponin Tup to 24 hour postoperativelyTroponin T difference in two groups
QTc intervalup to 24 hour postoperativelyOTc interval difference in two groups

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026