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Evaluation of Diagnoses and Clinical Outcomes in Children Undergoing MRI Scans

Evaluation of Diagnoses and Clinical Outcomes in Children Undergoing MRI Scans: a Retrospective, Longitudinal Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06278376
Enrollment
410
Registered
2024-02-26
Start date
2023-04-25
Completion date
2024-12-31
Last updated
2025-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Magnetic Resonance Imaging

Keywords

Magnetic Resonance Imaging, Childeren

Brief summary

The aim of this study is to evaluate the indications and therapeutical consequences of MRI scans of (young) children undergoing risky remote anaesthesia. The investigators want to aim for a clear indication in children undergoing MRI in the future before undergoing possible unnecessary procedures and MRI scans.

Detailed description

Magnetic resonance imaging (MRI) is a non-invasive imaging technique that allows physicians to visualize our anatomy, generating high-quality pictures of our body's internal structure at many different angles. The principle behind MRI, known as nuclear magnetic resonance (NMR), revolves around hydrogen atoms (or protons) that can be found everywhere in our entire body, such as in bones, blood, organs, skin, muscles and more. Protons have their own magnetic moment and angular momentum, allowing them to spin in a certain direction. By subjecting these spinning protons to a strong magnetic field they will be oriented along the axis of the magnetic field, either with or against the direction of the magnetic field. MRI machines generate this field using a large magnet surrounding the patient. Electric gradient coils allow the strength of the field to be adjustable, usually around 0,5 or 1,5 tesla. MRI has many advantages compared to other imaging techniques, i.e. CT (computed tomography), including the lack of radiation, the ability to show abnormalities of soft tissues, the ability to visualize blood flow, and contrasting agents that are less likely to cause adverse effects like allergic reactions. There are also some disadvantages or limitations, however: implants or metallic objects inside the body can make images unclear at best or harm the patient at worst; similarly, movements made by the patient can make images unclear as well. Lastly, MRI is a more expensive and slower technique compared to other imaging techniques. Children undergoing an MRI are often sedated before being placed inside the machine. After the scan is over, the children will be brought to a recovery area, where they can slowly recover from the sedation until they are fully awake again. Some common side effects resulting from the sedation may be vomiting, drowsiness and/or dizziness. The aim of this study is to evaluate the indications and therapeutical consequences of MRI scans of (young) children undergoing risky remote anaesthesia. The investigators want to aim for a clear indication in children undergoing MRI in the future before undergoing possible unnecessary procedures and MRI scans.

Interventions

None listed

Sponsors

Jessa Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Months to 16 Years
Healthy volunteers
No

Inclusion criteria

* Children undergoing an MRI scan in Jessa hospital (Hasselt, Belgium) between November 2016 and February 2023. * Age between 6 months and 16 years

Exclusion criteria

* /

Design outcomes

Primary

MeasureTime frameDescription
IncidenceBetween 2016 and 2023Incidence of diagnostic MRI in childeren

Secondary

MeasureTime frameDescription
Therapeutical implications: treatmentBetween 2016 and 2023Evaluating if the MRI investigation resulted in treatment (drug treatment, surgery or physiotherapy)
Clinical indicationsBetween 2016 and 2023Evaluating the clinical indications for the MRI investigation
Evaluation of body partBetween 2016 and 2023Evaluating which specific body parts are undergoing imaging
Evaluation of symptomsBetween 2016 and 2023Evaluation of the pre-existing symptoms (vomiting, headache, developmental delay, sleep issures, swellings, seizures, balance problems, conduct disorders, febrile convulsions) that potentially lead to an MRI scan
Clinical outcome: adverse eventBetween 2016 and 2023Evaluation of the clinical outcome: adverse events
Therapeutical implications: diagnosisBetween 2016 and 2023Evaluating the presence of a diagnosis after this MRI investigation
Clinical outcome: admission to hospitalBetween 2016 and 2023Evaluation of the clinical outcome: admission to hospital
Clinical outcome: mortalityBetween 2016 and 2023Evaluation of the clinical outcome: mortality after MRI
Evaluation of ageBetween 2016 and 2023Evaluation of age in children: \<2 years, 2-6 years and \>6 years
Influence of COVID-19 pandemicBetween 2016 and 2023Influence of COVID-19 pandemic (2020-2021 versus 2016-2017-2018-2019-2022-2023) on incidence, therapeutical implications and outcomes of MRI scans in children
Clinical outcome: surgeryBetween 2016 and 2023Evaluation of the clinical outcome: surgery after MRI

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026