Acute Aortic Syndrome, Acute Coronary Syndrome
Conditions
Brief summary
The goal of this observation study is to compare VOCs in cardiogenic chest pain population/health conditions, to answer：Establishment and promotion of the application system of emergency rapid detection of expiratory Volatile Organic Compounds (VOCs) in patients with acute cardiogenic chest pain 1. VOCs levels were measured at baseline in healthy people, and markers of VOCs that could be used to identify acute cardiogenic chest pain were sought. 2. The relationship between abnormal VOCs (mainly aldehydes) and prognosis of patients and the correlation with Super-score for early warning of acute heart failure.
Interventions
DIAGNOSTIC_TESTVOCs
test the end-expiratory gas
Sponsors
Qilu Hospital of Shandong University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Observation group inclusion criteria: 1. Over 18 years old, male or female; 2. Patients with acute cardiogenic chest pain (see diagnostic criteria); 3. Patient's informed consent. Inclusion criteria of healthy control group: 1. Over 18 years old, male or female; 2. Centerless cerebrovascular disease, lung disease, no abnormal liver and kidney function, no acute infection recently; 3. Informed consent.
Exclusion criteria
1. The patient had difficulty in collecting breath; 2. Patients with terminal illness or receiving palliative care; 3. Have participated in other clinical studies or consider it inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline VOCs (aldehydes) levels in healthy population | Baseline | Baseline VOCs (aldehydes) levels in healthy population |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| MACE in patients with cardiogenic chest pain | From enrollment to the end of treatment at 30 days | the relationship between the different VOCs levels and 30-day MACE in patients with cardiogenic chest pain |
Countries
China
Contacts
Primary ContactYuan Bian, Dr.
Backup ContactXiuting Yang, Dr.
Outcome results
None listed