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Hair Cortisol and Symptoms in Children With Psychopathology During CBT

Association Between Hair Cortisol and Symptoms in Children With Psychopathology During CBT

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06274424
Enrollment
100
Registered
2024-02-23
Start date
2016-07-01
Completion date
2019-10-01
Last updated
2024-02-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child Behavior Problem

Keywords

Children, group cognitive behavioral therapy, hair cortisol concentration, internalizing symptoms, externalizing symptoms, sleep disturbance symptoms

Brief summary

This study aims to examine the relationship between hair cortisol concentration and behavior and sleep disturbance symptoms in children with psychiatric disorders. It also investigates potential changes in hair cortisol and symptomatology after group-based cognitive behavior therapy. Furthermore, the study explores the effects of any alterations in hair cortisol concentration levels on potential behavior and sleep disturbance symptom change over the course of the study.

Interventions

A group CBT intervention comprising ten weekly 60-minute sessions followed by two booster sessions.

Sponsors

Helsinki University Central Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Years to 13 Years
Healthy volunteers
No

Inclusion criteria

* symptoms of anxiety or depression * deficiencies in emotional and behavioral skills impairing functioning * sufficient social and cognitive skills to participate in group work.

Exclusion criteria

* excessive physical aggression * excessive physical restlessness * severity of psychiatric symptoms requiring individual psychotherapy (e.g., acute suicidality).

Design outcomes

Primary

MeasureTime frameDescription
Hair Cortisol ConcentrationBefore and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-upLevel of hair cortisol concentration measured from hair samples
Parent- and teacher rated internalizing and externalizing symptomsBefore and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-upThe Achenbach System of Empirically Based Assessment (ASEBA). Scores below 60 reflect the normal range, scores from 60 to 63 the borderline range, and scores above 63 the clinical range
Child-rated internalizing symptomsBefore and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-upThe Spence Children´s Anxiety Scale. A total score of 60 or higher is indicative of elevated anxiety.
Parent-rated sleep disturbance symptomsBefore and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-upSleep Disturbance Scale for Children (SDSC). A cutoff score of 39 and above has been suggested to identify children with sleep disturbance.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026