Laparoscopic Surgeries
Conditions
Keywords
flow controlled ventilation, laparoscopy
Brief summary
It is aimed to investigate the effect of flow controlled ventilation on intraoperative respiratory parameters and hemodynamic parameters in laparoscopic operations.
Detailed description
Study will begin after ethics committee approval and the patient's written and verbal consent . Prospective observational studies will be conducted on patients over the age of 18 who will undergo laparoscopic surgery in the operating rooms. Patients who did not give verbal and written consent, emergency interventions, patients at risk of aspiration, patients with an ASA physical status above 3 and a diagnosis of COPD will be excluded. Patients will be randomized and divided into two groups. Patients intraoperatively ventilated with a conventional ventilator (GE™ Avance™ CS2, VCV mode) Group 1, intraoperative ventilation Ventinova ( Evone®, Ventinova Medical, Eindhoven, the Netherlands, FCV mode) will be referred to as Group 2. Standard monitoring (ECG; SpO2, end tidal CO2,arterial blood pressure) will be applied to all patients. Anesthesia induction will be performed with propofol, fentanyl, rocuronium bromide as standard; In addition, anesthesia maintenance of the patients will be provided with propofol and remifentanil. Respiratory parameters such as peripheral SpO2, PaCO2 value, peak airway pressure of each group will be recorded, and intraoperative hemodynamic parameters (systolic, diastolic, mean blood pressure, heart rate) of each group will be monitored and recorded. Postoperative respiratory functions and length of hospital stay of all patients will be monitored and recorded.
Interventions
effects of flow controlled ventilation
effects of volume controlled ventilation
Sponsors
Derince Training and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
patients who will undergo laparoscopic surgeries, ASA 1,2,3 physical status \-
Exclusion criteria
* patients who do not give verbal and written consent, emergency interventions, patients at risk of aspiration, patients with an ASA physical status above 3 and a diagnosis of COPD
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effects of flow controlled ventilation on arterial pressure | intraoperatively | Arterial blood pressure in mmHg |
| effectcs of flow controlled ventiletion on endtidal CO2 | intraoperatively | endtidal CO2 in mmHg |
| effects of flow controlled ventilation on mean arterial pressure | intraoperatively | mean arterial pressure change in percent |
| effects of flow controlled ventilation on heart rate | intraoperatively | heart rate in bpm |
| effectcs of flow controlled ventiletion on peak airway pressure | intraoperatively | peak airway pressure in cmH2O |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| respiratory related complications | intraoperative period and postoperative first week | rate of ventilator-associated pneumonia, rate of postoperative atelectasis, respiratory distress requiring reintubation by percentage. |
Countries
Turkey (Türkiye)
Outcome results
None listed