Esophagectomy, Pneumonectomy, Lobectomy
Conditions
Keywords
Esophagectomy, Pneumonectomy, Lobectomy, Stellate Ganglion Block
Brief summary
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of postoperative atrial fibrillation as compared to standard of care.
Interventions
DRUG0.5% bupivacaine
an ultrasound guided left stellate ganglion block with 5 mL of 0.5% bupivacaine
OTHERSaline
an ultrasound guided left stellate ganglion block with 5 mL of saline
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Masking description
This is a double blind randomized prospective controlled trial. Randomization will be 1:1.
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing esophagectomy, pneumonectomy, or lobectomy aged 18-85.
Exclusion criteria
* Patients who have an exclusion to regional anesthesia. * Patients who have exclusion to stellate blockade. * Patients who are pregnant assessed via self-report or pregnancy test if they have taken one
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| an ultrasound guided left stellate ganglion block with 5 mL of saline. | 168 hours after surgery | Incidence of Atrial fibrillation in the first 168 hours after surgery. |
| Atrial fibrillation; Other arrhythmias; Adverse events. | 168 hours after surgery | Atrial fibrillation in first 24, 48, 72, 96, 120, and 144 hours; Other arrhythmias in first 24, 48, 72, 96, 120, 144 and 168 hours; Adverse events. |
Countries
United States
Contacts
Primary ContactCandace Nelson
Outcome results
None listed