hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical Periodontitis

Effect of Endodontic Treatment on Serum High Sensitivity C-reactive Protein and Complete Hemogram Indices in Patients With Cardiovascular Disease With and Without Apical Periodontitis: A Prospective Interventional Study

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06270693

Enrollment

Registered

2024-02-21

Start date

2022-11-01

Completion date

2024-04-01

Last updated

2024-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apical Periodontitis, Coronary Artery Disease

Keywords

apical periodontitis, coronary artery disease

Brief summary

Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure.

Detailed description

Interventions

PROCEDUREEndodontic treatment

Root canal treatment

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Coronary artery disease patients with and without chronic pulp exposure

Exclusion criteria

* Other systemic diseases * Antibiotics for More than 1 month * Smoking * Analgesics more than 1 week

Design outcomes

Primary

Measure	Time frame	Description
Serum hsCRP	12 months	Systemic inflammatory burden assessed
complete hemogram indices	12 months	Systemic inflammatory burden assessed

Secondary

Measure	Time frame	Description
Periapical index SCORE CHANGE	12 months	1-5 ordinal scale,5 worse outconpme & HEALING ASSESSED

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026