Chemical Pollutants Exposure, Newborn, Sleep
Conditions
Keywords
sleep, Newborn, chemical pollutants exposure
Brief summary
During their first year of life, children spend more than half their time sleeping, a function essential to their neurodevelopment. This period of maturation and development of the future adult is considered extremely vulnerable to environmental exposure. During this period, the child's diet is mainly provided by breastfeeding, where persistent chemical substances have been found. A cocktail of 19 mostly persistent substances (POPs) present in breast milk has recently been identified as the main contributor to neurodevelopmental risk. However, the reality of their impact on neurophysiological development, in particular on infant sleep, has yet to be assessed. In this project, the sleep of children under 6 months of age will be studied using an actimetry watch worn for 7 days by the child, accompanied by a sleep diary. Exposure to environmental pollutants will be assessed by measuring their presence in the infant's milk (breastfeeding) and wearing a silicone bracelet to collect air pollutants. A questionnaire on exposure will complement this evaluation.
Interventions
DEVICE7-day actimetry sleep recording
7-day actimetry sleep recording
OTHERDetermination of environmental pollutants in breast milk
Determination of environmental pollutants in breast milk
OTHERMeasurements of environmental pollutants in indoor air deposited on the bracelet worn by the child
Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child
OTHERContinuous recording of the child's temperature for 7 days
Continuous recording of the child's temperature for 7 days
OTHERUse of a sleep diary for 7 days
Use of a sleep diary for 7 days
OTHERParental questionnaire of environmental exposure
Parental questionnaire of environmental exposure
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 6 Months
Healthy volunteers
No
Inclusion criteria
* Infant less than 6 months of age still on milk diet (total)
Exclusion criteria
* Infants with neurological or neurobehavioral disorders * Families who wish to relocate within 7 days of inclusion * Minor parents deprived of their parental rights, not understanding French, in a state of stress, overwhelmed or vulnerable. * Non-affiliation to a social security system
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total sleep time per day in infants using actimetry | 7 days | total sleep time per day (min)) in infants using actimetry |
Secondary
| Measure | Time frame |
|---|---|
| Concentration of various substances in breast milk | 1 day |
| concentration of chemical polluants on newborn bracelets | 1 day |
| Child Temperature level (°C) | 7 days |
Countries
France
Contacts
Primary ContactKaren CHARDON, Pr
Backup ContactElodie HARAUX, Pr
Outcome results
None listed