Diabetic Macular Edema, Macular Degeneration, Retinal Vein Occlusion
Conditions
Brief summary
The purpose of this study is to assess the sensation of ocular dry eye symptom after an intravitreal injection of anti-VEGF.
Detailed description
The recrutement of the patient is done during the inclusion of the patient by the nurses of the ophtalmological service of clermont-ferrand and confirm by an ophtalmologist of the service. A mesure of the OSDI is done before the injection, then at 1 day, on week by a phone call. Each of this mesures are done for the 2 other injections. Before each of this injection, a clinical mesure is done by a lacrydiag: the atrophy of the meibomian glands, the non-invasive break-up time, interferometry, the heigh of the tear meniscum.
Interventions
None listed
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient with exsudative age-related macular degeneration, diabetic macular edema or retinal vein occlusion * Patient with 3 ocular intravitreal injections of anti-VEGF in one eye
Exclusion criteria
* pregnant or breastfeeding woman * intravitreal injection before the study * intravitreal injection in both eyes * allergy of betadine * guardianship patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| OSDI | before the injection and at 1 day | Ocular Surface Disease Index: 12 questions treating of either the sensation, the visual impact and the environemental impact of the dry eye disease |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| HM | before each injection | MH: hauteur méniscal : high of meniscal tear film |
| AM | before each injection | Atrophie meibomienne: meibomian atrophy |
| OSDI | before the injection and at 1 week | Ocular Surface Disease Index: 12 questions treating of either the sensation, the visual impact and the environemental impact of the dry eye disease |
| NIBUT 2 | before each injection | Average Non Invasive Break-Up Time : average time when the tear film lose is regularity for each location |
| Interferometry | before each injection | Interferometry: High of the lipid film of the tear |
| NIBUT 1 | before each injection | First Non Invasive Break-Up Time: time when the tear film lose is regularity regardless of is location |
Countries
France
Contacts
Primary ContactLise LACLAUTRE
Outcome results
None listed