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Severity Over Time of Early Forms of Spondyloarthritis

Severity Over Time of Early Forms of Spondyloarthritis, a Prospective Observational Study.

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06261931
Acronym
STAR
Enrollment
387
Registered
2024-02-15
Start date
2024-02-12
Completion date
2044-02-28
Last updated
2024-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spondyloarthritis, Spondyloarthritis, Axial

Brief summary

Spondyloarthritis (SpA) is a group of chronic inflammatory pathologies whose progression over time is poorly defined, and in particular the clinical and instrumental elements that can predispose to a condition of disease severity are not completely known. It would be important to have an idea of what the predisposing factors are, possibly already at baseline, and possibly also at follow up, of severe disease, so as to be able to act early with more aggressive and targeted therapies on these patients, so as to achieve remission.

Interventions

DIAGNOSTIC_TESTDiagnostic assessment

patient with sponiloarthritis who comes to the clinic Hospital for clinical evaluation of disease. Assessment instrumental evaluation of the axial involvment t, with x-ray of the spine and pelvis every 5 years, and MRI of the spine and pelvis every 2 years.

Sponsors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* age >18 years; * Diagnosis of SpA confirmed by the rheumatologist with duration of symptoms < * 2 years; * Signature of the written informed consent to the study

Exclusion criteria

* Age < 18 years; * Patients suffering from other rheumatic pathologies (even in overlap), or genetic diseases such as Marfan syndrome, Ehlers Danlos syndrome * Any medical or psychiatric condition that in the judgment of the investigator would prevent the participant from complying with the protocol or completing the study according to the protocol. * Refusal to sign the informed consent to the study.

Design outcomes

Primary

MeasureTime frameDescription
spondyloarthritis severityt0 baseline 3hours, t1 3 months 3hours,t2 6 months 3hours,t2 12months 3hours,every six months up to the tenth yearevaluation of disease severity at 10 years in the entire study population

Countries

Italy

Contacts

Primary ContactMaria Antonietta D'Agostino, Professor
mariaantonietta.dagostino@policlinicogemelli.it+390630157807

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026