Healthy Lifestyle
Conditions
Brief summary
Minimally processed animal protein is a premier source of essential macro and micronutrients in the diet and is important, especially to older adults who are at increased risk of nutritional deficiency and age-related physiological changes. Our central hypothesis is that adding lean animal protein within a healthy diet following macronutrient recommendations for Americans will enhance nutrient adequacy and attenuate markers of cognitive decline. This is a retrospective study leveraging samples collected from the feeding trial NCT05581953. PI for both studies are the same.
Interventions
OTHERRed meat-based meal
Participants were provided with food as part of a meal plan. The research team provided all foods and snacks for the intervention.
OTHERNo meat diet
Participants were provided with food as part of a meal plan. The research team provided all foods and snacks for the intervention.
Sponsors
South Dakota State University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Generally, good health status based on one routine physical in the past 15 months, current health status * Normal HbA1C, weigh 110 lb or more * Age 65 years or more, generally healthy, all races and both sexes * Generally practicing a meat-based dietary pattern, do not have any special dietary requirements, and * Willingness to comply with the study protocol, including on-site meal consumption and sample/data collection.
Exclusion criteria
* Medication usage, probiotic, long-term antibiotic, and tobacco/drug/alcohol use * Not on any special diet within 3 months of recruitment, and do not intend to lose weight * Impaired kidney functions * Active history of cancer, diabetes, heart, liver, and kidney diseases * Major gastrointestinal disorders in the past 3 months * History of heart attacks or stroke * Unable to meet in-person visit requirements for dining, picking up meals, and tests * Any mental health condition affecting the ability to provide written informed consent * If they had not had a routine health checkup 12 months before recruitment. * If they were unwilling to abstain from taking nutritional supplements, alcohol, non-study foods, and beverages during the study period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Concentration of phosphatidylcholine in blood | 8 weeks | Using Microplate Assay |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORMoul Dey, Ph.D
South Dakota State University
Outcome results
None listed