Hemodialysis Patients With Sarcopenia
Conditions
Keywords
mindfulness meditation, progressive muscle relaxation, uremic sarcopenia, maintenance hemodialysis, quality of life
Brief summary
To study the effect of mindfulness meditation combined with progressive muscle relaxation training on clinical efficacy and quality of life in maintenance hemodialysis (MHD) patients with sarcopenia. Eligible sarcopenic patients in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group received mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks.To observe whether the combined intervention training can improve the motor ability and quality of life of patients with sarcopenia in a short period of time.
Interventions
BEHAVIORALThe mindfulness meditation combined with progressive muscle relaxation training .
The first part is progressive muscle relaxation training. The second part is mindfulness meditation training.
Sponsors
Ningbo Medical Center Lihuili Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients who met the sarcopenia criteria established by the Asian Working Group for Sarcopenia (AWGS) in 2014 * Stable condition and generally good health status * Good compliance and ability to collaborate well with the physician * Undergoing hemodialysis three times per week for at least three months, with a KT/V ≥ 1.2 * No significant cardiovascular or cerebrovascular complications (such as severe heart failure, severe arrhythmias, angina, and cerebrovascular diseases) * Patients with sarcopenia who met the clinical diagnostic criteria were selected to ensure the quality of the included patients
Exclusion criteria
* Inability to complete handgrip strength, 6-meter walk test, 10 sit-to-stand tests, and the use of bioelectrical impedance analysis (BIA) due to contraindications * Coexistence of mental illness or severe cognitive or communication disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 10 sit-to-stand test in seconds | 3 months | The 10 sit-stand test represents exercise ability, and the shorter the time, the greater the exercise ability. |
| Grip strength in kilograms | 3 months | Grip strength represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero, and its maximum value is unlimited. |
| 6-meter walk test in metre per second | 3 months | 6-meter walk test represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero metre per second, and its maximum value is unlimited. |
| KDQOLTM(Kidney Disease Quality of Life short Form) score | 3 months | The KDQOLTM score is between 0 and 100, and the higher the score, the better the health |
| interleukin-6 (IL-6) | 3 months | Interleukin 6 represents an inflammatory marker, and its concentration is 20pg/ml or less. |
| high-sensitivity C-reactive protein (hsCRP) | 3 months | hsCRP represents an inflammatory marker, and its concentration ranges from 0.0 to 10mg/L. |
| albumin(ALB) | 3 months | Albumin represents a nutritional indicator, and its concentration ranges from 40 to 55g/L. |
| prealbumin (PA） | 3 months | Prealbumin represents a nutritional indicator, and its concentration ranges from 0.20 to 0.43g/l. |
Countries
China
Outcome results
None listed