Hospitalized Children, Invasive Bacterial Infection, Severe Infection
Conditions
Brief summary
Severe bacterial infections are a worldwide scourge. However, the epidemiology of this type of infection varies over time. It is therefore essential to monitor them in order to prevent them more effectively. At this time, in France, no monitoring exists for this kind of infections.
Detailed description
The main aim of this study is to assess the number of cases and describe the clinical, biological and microbiological characteristics of these cases of severe communautary invasive bacterial infections in children hospitalized in pediatric intensive care units. In addition, the management of these hospitalized children will be described.
Interventions
None listed
Sponsors
Association Clinique Thérapeutique Infantile du val de Marne
GFRUP (Groupe Francophone de Réanimation et d'Urgences Pédiatrique)
Groupe de Pathologies Infectieuses Pédiatriques (GPIP)
Centre National de Référence des Streptocoques
Centre National de Référence des Pneumocoques
Centre National de Référence des Méningocoques et Haemophilus influenzae
Centre National de Référence des staphylocoques
Centre National de Référence des E. Coli
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Age \<18 years (only hospitalized children) * Severe communautary bacterial infection defined by hospitalization in a pediatric intensive care unit (documentation of infection by identification of the bacteria in a sterile environment).
Exclusion criteria
* Refusal by one of the parents or by Child in understanding age * Nosocomial infection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of pediatrics cases of severe communautary bacterial infections | 1 year | Proportion of hospitalized children in intensive care unit due to severe communautary bacterial infections |
| medical characterisation of children hospitalized for severe communautary bacterial infection case | 1 year | Assessment of clinical, biological and microbiological characteristics of hospitalized children in intensive care unit due to severe communautary bacterial infections cases |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Identify risk factors of serious infection | 1 year | Describe what is responsible of serious infection |
| Identify predictive signs of severe cases in infected children. | 1 year | what are the warning signs of a serious infection? |
| healthcare used for infected children | 1 year | Describe healthcare provided during hospitalisation of infected children in order to manage this type of infection |
| Type of complications | 1 year | Describe any complications due to infection |
| Patients outcome | 1 year | Proportion of patients recovered |
| treatment used during hospitalisation | 1 year | type of treatment used during hospitalisation to manage the infection |
| Bacterial strain characterization | 1 year | What bacterial strain is involved in the infection |
Countries
France
Contacts
CONTACTCorinne Levy
CONTACTstéphane Béchet
PRINCIPAL_INVESTIGATORMichael Levy
CHU Robert Debré, Paris
STUDY_DIRECTORCorinne Levy
Association Clinique Thérapeutique Infantile du val de Marne
Outcome results
None listed