Skip to content

Nutrition Under Noninvasive Ventilation

Nutrition Under Noninvasive Ventilation in Critically Ill Patients: a Retrospective Monocentric Analysis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06260202
Acronym
NUTRINIV
Enrollment
112
Registered
2024-02-15
Start date
2024-03-01
Completion date
2024-05-31
Last updated
2024-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Noninvasive Ventilation, Nutrition Therapy, Respiratory Insufficiency

Brief summary

Even though nutrition is a fundamental component of Intensive care unit (ICU) therapy, critically ill patients are frequently malnourished, a factor well known for its strong association with a higher risk of complications, prolonged ICU/hospital length of stay, and greater ICU readmission and mortality rates. Noninvasive ventilation (NIV) use has increased considerably over the past twenty years, making this supportive technique a keystone of acute respiratory failure (ARF) treatment. In this setting, respiratory support is provided through an interface, usually a mask or a helmet, that frequently represents an important obstacle to nutrition delivery, making oral intake impossible and posing the necessity to start enteral (EN) or parenteral nutrition (PN). Moreover, while critical care guidelines regarding nutritional management of patients receiving mechanical ventilation (MV) are well established, data and recommendations about the appropriate nutritional support to patients in NIV are still very limited. Due to this limited data, we want to describe characteristics and nutritional management of patients undergoing NIV in ICU, and to evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients. Secondarily, we want to evaluate the difference of the caloric and protein intake among groups of patients undergoing different nutritional modality and to assess potential associations of the nutritional characteristics with patient outcomes.

Interventions

None listed

Sponsors

Università degli Studi del Piemonte Orientale Amedeo Avogadro
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients; * Admission to the Intensive Care Unit of Maggiore della Carità University Hospital from March 1st 2020 to February 28th 2023; * Noninvasive ventilation treatment for acute respiratory failure of any cause; * Duration of noninvasive ventilation treatment of more than two days; * Informed consent signed.

Exclusion criteria

* Patients under 18 years of age; * Duration of noninvasive ventilation treatment of less than two days.

Design outcomes

Primary

MeasureTime frameDescription
Caloric and protein gapAt ICU discharge, a median of six daysto evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients for every day of ICU stay

Secondary

MeasureTime frameDescription
Nutrition modalities outcomesAt ICU discharge, a median of six daysto evaluate the difference of the mean caloric and protein intake among groups of patients undergoing different nutritional modality

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026