Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.

Antibody Response to Coronavirus Disease 2019 (COVID-19) Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06259656

Enrollment

Registered

2024-02-14

Start date

2023-10-25

Completion date

2023-11-25

Last updated

2024-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19

Keywords

Anti SARs-CoV, Pregnancy, Cordblood, Vaccine

Brief summary

The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.

Detailed description

The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV. Sample size is 40 Thai patients at labor room Vachira Phuket Hospital in October - November 2023, who have at least one COVID-19 vaccination before or when pregnant. The Secondary outcome is to study time effect after COVID-19 vaccination and effect of vaccine type on Antibody level.

Interventions

DIAGNOSTIC_TESTCOVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Maternal blood and cord blood were collected to test for COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Intervention model description

Thai term pregnant women are recruited at labor room, after informed consent was done. Characteristic data (such as vaccination type and time) and Maternal Blood was collected then cord blood was collected after birth. All blood was sent to test Anti SARs CoV antibody level. Then all data and 80 test result will analyzed.

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Thai term pregnant women * 18-45 year old * At least 1 covid vaccination received * admission at Vachira Phuket Hospital Labor Room

Exclusion criteria

* Do not want to participate * Unstable or Emergency condition

Design outcomes

Primary

Measure	Time frame	Description
COVID-19 Spike Protein IgG Quantitative Antibody (CMIA) Level	1 month	Test for correlation of level in maternal and cord blood

Secondary

Measure	Time frame	Description
Analysed time effect from last vaccination and type.	1 month	Test for time effect after last dose of vaccination

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026