Colorectal Cancer, ERAS
Conditions
Keywords
Colorectal Cancer, Hyper-ERAS, Super Accelerated Rehabilitation Surgery, Rapid Rehabilitation, Perioperative Management, ERAS2.0
Brief summary
This clinical trial aims to explore the safety and effectiveness of the Hyper-ERAS rehabilitation protocol for colorectal cancer patients and the feasibility of discharge within 48 hours.
Detailed description
The Hype-ERAS protocol includes preoperative education, intraoperative quality control, postoperative preventive analgesia, early ambulation, early recovery of diet, early removal of drainage tube, urinary catheter, and gastric tube, discharge within 48 hours after surgery, and standardized follow-up outside the hospital. Patients treated with the Hyper-ERAS rehabilitation protocol and discharged within 48 hours were in group A. Patients who were treated with Hyper-ERAS protocol and had a postoperative hospital stay of more than 48 hours were classified as group B. Patients eligible but not treated with the Hyper-ERAS rehabilitation protocol during the same period were in group C (Control group). The postoperative recovery of each group was compared to explore the safety and efficacy of Hyper-ERAS rehabilitation program in patients with colorectal cancer.
Interventions
PROCEDUREHyper-ERAS Program
Patients who met the inclusion criteria were treated with Hype-ERAS protocol, including preoperative education, intraoperative quality control, postoperative preventive analgesia, early ambulation, early recovery of diet, early removal of the drainage tube, urinary catheter, and gastric tube, and discharge within 48 hours or more than 48 hours safter surgery, and closely and standardized follow-up outside the hospital.
Sponsors
Peking University Cancer Hospital & Institute
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 79 Years
Healthy volunteers
No
Inclusion criteria
1. Pathologically confirmed colorectal cancer. 2. The position of the anastomosis is above the peritoneal reflection. 3. Age range from 18 to 79 years old. 4. No surgical contraindications. 5. The patient has good compliance and can understand the concept of rapid recovery. 6. Possess basic nursing conditions outside the hospital, and can arrive at the hospital within 30 minutes after discharge.
Exclusion criteria
* The
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 30-day overall complication rate | 30 days after surgery | The primary endpoint was the 30-day overall complication rate. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Severe complications (CD≥IIIb) rate, within 30 days after surgery | 30 days after surgery | Severe complications (CD≥IIIb) rate |
| The rehospitalization rate within 30 days after surgery | 30 days after surgery | — |
Countries
China
Contacts
Primary ContactChanglong Li
Backup ContactLin Wang, M.D.
Outcome results
None listed