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Virtual Reality in Motor Neurone Disease

Exploring the Use of Virtual Reality Applications in Patients With a Diagnosis of Motor Neurone Disease

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06256107
Acronym
VR in MND
Enrollment
6
Registered
2024-02-13
Start date
2021-01-13
Completion date
2023-10-31
Last updated
2024-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motor Neuron Disease

Brief summary

Motor Neurone Disease (MND) is a chronic progressive neurological condition where people experience weakness of muscles leading to pain and restriction of movement as well as problems with swallowing, breathing and communication. The purpose of this study is to establish if Virtual Reality is useful for people with MND and if it helps improve their well being.

Detailed description

Motor Neurone Disease (MND) is a chronic progressive neurological condition where people experience weakness of muscles leading to pain and restriction of movement as well as problems with swallowing, breathing and communication. As people become increasingly immobile, they become restricted in their ability to perform activities of daily living, access the outdoors, participate in preferred occupational roles or engage in leisure activities. Consequently, there is a deterioration in their ability to experience well being and have quality of life. There is also a significant carer burden as the carer spends long hours in the day looking after the person. The average disease trajectory lasts between 3-5 years, followed by death. More recently, the use of Virtual Reality (VR) technology is being recognised in the field of health. This technology uses the interactions between an individual and a computer generated environment to stimulate different sensory modalities such as visual and auditory. The technology can be accessed commonly using head mounted goggles or head sets. The entertaining or stimulating effect of VR is useful in redirecting the person's attention away from the distressing experiences, such as pain and anxiety. The purpose of this study is to establish if VR is useful for people with MND and if it helps improve their well being.

Interventions

DEVICEVirtual Reality Headset

Virtual Reality Headset

Sponsors

Lancashire Teaching Hospitals NHS Foundation Trust
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

Device Feasibility

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1. Diagnosis of MND 2. Sufficient cognitive ability to understand instructions with regards using the VR kit (ECAS score - minimum 100/136) 3. Has sufficient motor ability/dexterity to use the kit or a carer who will be able to assist with the use of the kit. 4. Can tolerate light and have sufficient head control to wear the head set. 5. English speaking

Exclusion criteria

1. Poor cognition - inability to understand instructions regarding the use of VR (Total ECAS Score \<100/136) 2. Unable to tolerate light/unable to wear the head set 3. Light sensitive epilepsy, severe vertigo or dizziness. 4. Non English speaking

Design outcomes

Primary

MeasureTime frameDescription
Edinburgh Mental Well being Scale4 weeksQuality of Life (Scale 0-10 higher being better)

Secondary

MeasureTime frameDescription
ECAS (Edinburgh Cognition Assessment Scale)4 weeksCognition measure scale varied per question (Scale 0-8, 0-10, 0-12 higher being better)
PHQ-94 weeksscale for depression (Scale 0-27 - higher being worse)
GAD-74 weeksscale for anxiety (Scale 0-3 where higher is worse outcome)
ALS-FRS4 weekstest of function (Yes or No - ability to perform function)

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026