Systemic Lupus Erythematosus
Conditions
Keywords
Depression -Anxiety-Anti-Ribosomal P Protein Antibody - Anti-U1 Antibody - Anti-Nucleosome Antibody - Anti-Double Strad DNA Antibody
Brief summary
the study determine the relation between the degree of (Depression and Anxiety) in Systemic Lupus Erythematosus Patients by zung self rating depression scale and zung self rating anxiety scale and (Anti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-Double Strad DNA Antibodies).
Interventions
DIAGNOSTIC_TESTAnti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-Double Strad DNA Antibodies
determine Anti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-Double Strad DNA Antibodies) and its relation to the degree of Depression and Anxiety in Systemic Lupus Erythematosus Patients
Sponsors
Sohag University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. Patients who fulfill the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria or 2019 American College of Rheumatology/European League against Rheumatism classification criteria of Systemic Lupus Erythematosus. 2. Patients who is able to give informed consent to join the study.
Exclusion criteria
* \- Any patient with any autoimmune disease other than systemic lupus erythematosus.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the degree of depression | 1 year | by using zung self-rating depression scale |
| the degree of anxiety | 1 year | by using zung self-rating anxiety scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anti-Ribosomal P Protein antibody | 1 year | was examined by ANA profile by immunoblot based assay with which the plasma of heparin-anticoagulated venous blood and there of IgG antibodies reacted against the auto-antigens are tested. |
| Anti-U1 RNP antibody | 1 year | was examined by ANA profile by immunoblot based assay with which the plasma of heparin-anticoagulated venous blood and there of IgG antibodies reacted against the auto-antigens are tested. |
| Anti-Nucleosome antibody | 1 year | was examined by ANA profile by immunoblot based assay with which the plasma of heparin-anticoagulated venous blood and there of IgG antibodies reacted against the auto-antigens are tested. |
| Anti-Double Strad DNA Antibody | 1 year | was examined by ANA profile by immunoblot based assay with which the plasma of heparin-anticoagulated venous blood and there of IgG antibodies reacted against the auto-antigens are tested. |
Countries
Egypt
Contacts
Primary ContactOsama S Daif Allah, Assistant Professor
Backup ContactHeba M Kamaly, Assistant lecture
Outcome results
None listed