Acne Vulgaris
Conditions
Brief summary
The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in treatment of acne vulgaris patient or not. Patients will be asked to take doxycycline along with tropical treatment in one group and metformin along with tropical treatment in another group. Researcher will compare the clinical improvement in two groups.
Interventions
DRUGMetformin and doxycycline
Metformin 500 mg tablet twice daily
Sponsors
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Newly diagnosed moderate and severe AV patients diagnosed by a dermatologist \-
Exclusion criteria
* Patients receiving topical retinoids within last two months * Pregnancy and lactation * History of corticosteroids intake * Suffering from malignancy or any cosmetic induced acne
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Global Acne Grading System (GAGS) Score | 12 weeks | Acne Vulgaris Severity assesment by GAGS score |
Countries
Bangladesh
Contacts
Primary ContactMuhammad Marnush, MBBS
Outcome results
None listed