High Vitamin K Intake Diet Intervention Effect on Cardiovascular Risk Percentage in Young Adults

Effect of Dietary Intervention With a High Intake of Vitamin K on Insulin, Osteocalcin, Leptin, Vitamin K Serum Levels and Cardiovascular Risk in Young Adults With and Without Overweight or Obesity.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06250647

Acronym

VKDI

Enrollment

Registered

2024-02-09

Start date

2021-02-06

Completion date

2021-08-16

Last updated

2024-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and Obesity

Keywords

Vitamin K, diet intervention, Cardiovascular disease, overweight and obesity, young adults

Brief summary

The goal of this clinical trial is to compare the effect of a high vitamin K diet intervention on vitamin K, insulin, osteocalcin serum levels and the cardiovascular risk percentage in normal weight and overweight or obese young adults. The main questions it aims to answer are: • Does a diet intervention containing 500mcg of vitamin K increases serum vitamin K levels? • Are vitamin K serum levels after the 500mcg of vitamin K diet intervention associated with insulin and osteocalcin serum levels or the cardiovascular risk percentage in normal weight and overweight or obese young adults? Participants will have to follow a diet intervention that contains 500mcg of vitamin K, given as a cyclic menu for 6 weeks. Also, participants will have to assist weekly to nutritional monitoring and to report any situation they observed regarding the intervention during this study. Researchers will compare normal weight and overweight or obese groups with diet intervention with normal weight and overweight or obese groups without diet intervention and only dietetic recommendations to see if vitamin K serum levels, insulin, osteocalcin and the cardiovascular risk percentage improve after the 6 weeks diet intervention.

Interventions

OTHERvitamin K diet

500mcg of Vitamin K intake provided by the selection of vitamin k rich foods in the menu.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* young adults * acceptation for participate * acceptation to asist to monitoring sessions * sign information consent

Exclusion criteria

* under other dietetic intervention * under medications that interfere with vitamin K or diminish its absorbtion * vitamin E or A intake supplements * previous diagnose of metabolic syndrome, diabetes mellitus, hypertension, cancer or dyslipidemia. * chronic alcohol intake * some medical or health situation that impedes the following of the program

Design outcomes

Primary

Measure	Time frame	Description
vitamin K serum levels	basal and after 6 weeks of diet intervention	ng/mL
Cardiovascular Risk Percentage	basal and after 6 weeks of diet intervention	percentage (%)
insulin serum levels	basal and after 6 weeks of diet intervention	mcUI/L

Secondary

Measure	Time frame	Description
Osteocalcin	basal and after 6 weeks of diet intervention	ng/mL

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026