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Dynamic Ultrasound of the Calf Muscles After Stroke

Het Gebruik Van Dynamische Echografie om Spier-pees Veranderingen te Onderzoeken in de Kuitspieren Van Personen na Een CVA: Een Pilootstudie

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06250478
Acronym
Stroke_DynUS
Enrollment
13
Registered
2024-02-09
Start date
2024-02-27
Completion date
2024-04-04
Last updated
2024-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gait Disorders, Neurologic, Stroke

Brief summary

Muscle behaviour of calf muscles can be studied during dynamic conditions using dynamic ultrasound. In particular, the medial gastrocnemius is suitable for measurements with dynamic ultrasound due to its superficial location. With this measurement technique, the muscle behavior during walking can be observed gaining insight into the mechanism of action of this muscle during a functional task. This technique has already been used in other populations (such as children with cerebral palsy) but not yet in individuals after a stroke. Therefore, the aim of this study is to assess the muscle behavior of the medial gastrocnemius during walking in persons after stroke. There are 3 concrete objectives of the current study: 1. is the technique feasible to perform in persons after stroke? 2. does the use of the dynamic echoprobe change gait patterns? 3. can differences between persons after stroke and healthy controls be detected? This data can be used as pilot data for project applications in the future that will allow to design larger studies. Therefore, 10 stroke patients and 10 age- and gender-matched healthy controls will walk on a treadmill for 3x2 minutes after a familiarisation period of 6 minutes. During 1 x 2 minutes, subjects will walk without using the dynamic ultrasound. This recording aims to measure the normal gait pattern of the subjects. During the other 2x2 minutes, subjects will walk using the dynamic ultrasound at 2 different locations on the calf. Once with the ultrasound probe on the centre of the muscle belly to visualise muscle fibre bundles and once on the muscle tendon transition, from which muscle belly and tendon length can be derived. The use of ultrasound or not will be randomized to exclude the effect of fatigue on the outcome measures.

Interventions

DIAGNOSTIC_TESTDynamic ultrasound of the calf muscles

Dynamic changes of the calf muscles during walking will be assessed in persons after stroke and compared to healthy controls

Sponsors

University Ghent
CollaboratorOTHER
University Hospital, Ghent
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

Both stroke patients and age and gender matched healthy controls will be included

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

Stroke group Inclusion criteria * stroke adults * no other neurologic conditions * ability to walk independently on a treadmill

Exclusion criteria

* wearing ankle foot orthosis that inhibit the assessment * had lower limb surgery in the past Healthy volunteers Inclusion criteria \- healthy adults

Design outcomes

Primary

MeasureTime frameDescription
Fascicle dynamics measured with ultrasound during walkingsingle point assessment in one day during walking with the probeLengthening and shortening of the fascicles of the medial gastrocnemius
Muscle belly dynamics measured with ultrasound during walkingsingle point assessment in one day during walking with the probeLengthening and shortening of the muscle belly of the medial gastrocnemius
Tendon dynamics measured with ultrasound during walkingsingle point assessment in one day during walking with the probeLengthening and shortening of the tendon of the medial gastrocnemius

Secondary

MeasureTime frameDescription
stance phasesingle point assessment in one day during walking with the probetime spend standing on the paretic and non-paretic leg (s) during walking
gait speedsingle point assessment in one day during walking with the probewalking velocity (m/s)
lower limb kinematicssingle point assessment in one day during walking with the probejoint angles (°) in the pelvis, hip, knee and ankle in the sagittal, frontal and transverse plane during walking
swing phasesingle point assessment in one day during walking with the probetime spend not standing on the paretic and non-paretic leg (s) during walking
step widthsingle point assessment in one day during walking with the probestep width (m)
Step lengthsingle point assessment in one day during walking with the probeStep length (m) of the paretic and non paretic side

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026