Contained Hepatic Vascular Injuries Following Liver Trauma

Contained Hepatic Vascular Injuries Following Liver Trauma: a Retrospective Monocentric Study and Review of the Literature

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06249646

Enrollment

318

Registered

2024-02-08

Start date

2022-01-01

Completion date

2023-03-31

Last updated

2024-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic Injury, Liver Injury, Pseudoaneurysm

Brief summary

Background: For thirty years, a major shift in the management of liver trauma has been seen. Contained hepatic vascular injuries (CHVI), including pseudo aneurysms and arteriovenous fistula, are often feared due to their risk of secondary bleeding. Nonetheless, knowledge of CHVI is scarce and no guidelines on their management have been set. The investigators aimed to validate the risk factors of CHVI, identify associated morbidities, and establish a management protocol. Study Design: A retrospective study on 318 liver trauma from a level 1 trauma center over the last 15 years, comparing the presence or not of CHVI. Univarious and multivarious analyses were performed. A comparison of the management of CHVI was also performed.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Inclusion criteria

* presence of liver trauma * age above 15 years old * a full contrast abdominal CT

Exclusion criteria

none

Design outcomes

Primary

Measure	Time frame	Description
Identification of a % of CHVI on the initial or the follow-up Chest-Thorax scans.	6 months	A junior and a senior radiologist reviewed all initial and follow-up CT scans, blinded from the diagnostic. Contained hepatic vascular injuries (CHVI) was defined as Hepatic Pseudoaneurysm (HPA) and/or arterio-venous fistula (AVF), under the American Association for Surgery of Trauma (AAST) organ injury scale (2018 revision) for liver trauma definition: a contained focal collection of vascular contrast which decreases in attenuation on delayed phase images on contrast-enhanced CT

Secondary

Measure	Time frame	Description
Investigate the management of CHVI following liver trauma.	6 months	size in millimeters of pseudoaneurym conducting to angio-embolization

Countries

France

Outcome results