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Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06249568
Acronym
fluidresponse
Enrollment
45
Registered
2024-02-08
Start date
2023-06-01
Completion date
2024-08-20
Last updated
2024-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Bypass Surgery Patients, Fluid Therapy, Lung Recruitment Maneuver

Keywords

fluid therapy, Coronary Artery Bypass Surgery Patients, Lung Recruitment Maneuver

Brief summary

Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass surgery, it is useful to predict fluid responsiveness after sternotomy in coronary artery bypass surgery patients ventilated with 6 ml/kg PBW (ideal body weight). We aimed to reveal the sensitivity and specificity of PPV and SVV changes by applying a lung opening maneuver.

Detailed description

In order to evaluate the fluid deficit in patients undergoing coronary artery bypass surgery, researchers will measure stroke volume index, cardiac index and mean arterial pressure while the patients are in the lima position. Then researchers will perform a lung opening maneuver (30mmHg for 30 seconds) and measure again. researchers will measure again after the values return to normal. researchers will give patients balanced fluid at 3ml/kg and record their values. Can researchers predict fluid response with lung opening maneuver?

Interventions

None listed

Sponsors

Ankara City Hospital Bilkent
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Inclusion Criteria: * 1-ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia *

Exclusion criteria

* 1\. Be younger than 18 years old, be over 80 years old * 2\. Patients with an ASA score greater than 3 * 3\. EF\<40% * 4\. Those with contraindications to anesthetic drugs * 5\. Patients with BMI\>30 * 6\. Patients who did not want to participate in the study * 7\. Right ventricular dysfunction * 8\. COPD(Chronic obstructive pulmonary disease) * 9\. Bullous lung disease * 10\. Moderate to severe PHT * 11\. Severe kidney or liver disease * 12\. Patients with hemodynamic instability in the perioperative period * 13\. Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Determination of fluid responsiveness in patients undergoing coronary arter bypass surgery.from start to 4 months: Demonstration of fluid responsiveness in patients who will undergo coronary artery bypass surgery will prevent unnecessary fluid administration in case of hemodynamic disturbance, and medical treatments and interventions can be performed in a timely and targeted manner. Researchers will perform a recruitment maneuver on the patients and record mean arterial pressure and stroke volume index. Researchers will perform a recruitment maneuver on the patients and record mean arterial pressure and stroke volume index. Afterwards, researchers will give 3ml/cc balanced fluid to the patient and record the change in mean arterial pressure and stroke volume index.

Countries

Turkey (Türkiye)

Contacts

Primary Contactmeltem sakman yılmaz
meltemsakmann@gmail.com+90 505 922 1049

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026