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Feasibility of TEE During Cardiac Arrest in Dutch Emergency Departments

Feasibility of Transesophageal Echocardiography in Patients With Cardiac Arrest in Emergency Departments in the Netherlands

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06249035
Enrollment
30
Registered
2024-02-08
Start date
2024-06-25
Completion date
2025-05-01
Last updated
2024-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

transoesophageal echocardiography, POCUS, Emergency Department

Brief summary

The goal of this feasibility study is to learn if Dutch ED providers are able to use transesophageal echocardiography during cardiac arrest. The main question it aims to answer is: • are the ED providers able to determine the area of maximal compression of the heart using TEE

Detailed description

Point-of-care ultrasound is a valuable diagnostic tool during cardiopulmonary resuscitation (CPR) in cardiac arrest and its use is recommended by international guidelines. Transthoracic echocardiography (TTE) is most commonly used, but has certain limitations. Image acquisition can be challenging due to patient specific factors such as body habitus. Also image quality may be impacted by the limited acquisition time during CPR pulse checks. Furthermore, observational data suggests that pulse checks are prolonged due to TTE, while minimizing interruption of chest compressions is emphasized for better CPR outcomes in the guidelines. Transesophageal ultrasound (TEE) is a possible alternative for TTE. It has the theoretical advantage of superior image quality and thereby possible reductions of chest compression delays. Furthermore, TEE gives the opportunity determine which part of the heart is compressed most effectively, which is referred to as the area of maximal compression (AMC). Animal studies showed that an AMC located over the left ventricle positively influenced hemodynamics and return of spontaneous circulation (ROSC) compared to an AMC over the aortic root. In human studies, data also suggests that AMC located on the left ventricle, as measured by TEE, may positively influence prognosis. In the Netherlands, TEE is currently not used in emergency departments during cardiac arrest. The purpose of this study is to investigate if point-of-care TEE can be used effectively and safely by providers and teams that have not previously used this modality. Given the paramount importance of quality of chest compressions, the ability of the providers to assess the location of the AMC will be the main focus of this feasibility study.

Interventions

DIAGNOSTIC_TESTTransoesophageal echocardiography (TEE)

TEE is a diagnostic modality in which an ultrasound probe is inserted via the oesophagus in order to visualize the heart.

Sponsors

Onze Lieve Vrouwe Gasthuis
CollaboratorOTHER
Frisius Medisch Centrum
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

TEE will be performed on all patients that are eligible for inclusion.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with cardiac arrest \> 18 year in the emergency department.

Exclusion criteria

* Patients with known upper gastro-intestinal malignancy or strictures, previous upper gastro-intestinal surgery or radiation, or known esophageal varices. * Patient with a do-not-resuscitate order, pregnant patients and traumatic cardiac arrest. * No trained TEE provider available. * ROSC at arrival. * Decision by the team to stop resuscitation at arrival at the emergency department due of prognosis. * Other life saving interventions which are prioritized over TEE by the resuscitation team.

Design outcomes

Primary

MeasureTime frameDescription
Area of maximal compression (AMC)First 30 minutes of cardiac arrest treatment in the ED.The percentage of patients in which providers are able to determine the location of the AMC during cardiac arrest.

Secondary

MeasureTime frameDescription
Location of AMCFirst 30 minutes of cardiac arrest treatment in the ED.The echographic location of the AMC, subcategorised as: left ventricle, left ventricular outflow tract/aortic root, other, not able to determine AMC
Accuracy of AMCFirst 30 minutes of cardiac arrest treatment in the ED.Accuracy of AMC defined as correlation between providers interpretation of AMC and reviewers interpretation of AMC
Safety of TEEFirst 30 minutes of cardiac arrest treatment in the ED.Incidence of complications of TEE
IntubationFirst 30 minutes of cardiac arrest treatment in the ED.Need for intubation for using TEE and duration of intubation
Time to imageFirst 30 minutes of cardiac arrest treatment in the ED.Time from start ED treatment to first TEE image

Countries

Netherlands

Contacts

Primary ContactPeter Veldhuis, MD
peter.veldhuis@mcl.nl+3158 286 6666

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026