Post-Acute COVID-19 Syndrome
Conditions
Keywords
Post-Covid 19 Syndrome, Covid-19, fatigue, cardiovascular system, respiratory system, rehabilitation
Brief summary
The objective of the study is to compare the acute cardiorespiratory and perceptual responses to a physical exercise session in those infected by Covid-19 with and without persistent symptoms.
Detailed description
The study will be a crossover carried out in two groups (with and without persistent symptoms of Covid-19). Participants in both groups will undergo a control session and an exercise session and cardiorespiratory and perceptual responses will be obtained before, during and after the sessions. In the exercise session, participants will perform aerobic exercises, strength exercises and muscle stretching, while in the control session participants will remain seated. Blood pressure, heart rate, cardiac autonomic modulation, peripheral oxygen saturation, vascular function and perception of affect will be obtained.
Interventions
BEHAVIORALExercise session
Session will included aerobic, resistance and flexibility exercises and will last approximately 45 minutes. The session will begin with aerobic exercises (5 min jumping jacks and 5 min stationary walking). Then, nine strength exercises will be performed for the main muscle groups (3 times of 12 to 15 repetitions, with a 1-minute rest interval) and finally stretching for the main muscle groups
BEHAVIORALControl session
Remain seated for 60 min
Sponsors
University of Nove de Julho
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Post-Covid Syndrome group: * have had a positive RT-PCR test for Covid-19; * present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO); * have the cognitive and physical capacity to perform the exercises; It is * low cardiovascular risk classification according to the American College of Sports Medicine criteria. Healthy group: * not present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO); * have the cognitive and physical capacity to perform the exercises; It is * low cardiovascular risk classification according to the American College of Sports Medicine criteria.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Heart rate variability | Before and 30 and 50 minutes after the end of the exercise and control interventions | Assessment of the heart rate variability indicators using a heart rate monitor |
| Change in peak exhalation flow | Before and 5 minutes after the end of the exercise and control interventions | Assessment of the peak exhalation flow using a peak flow device |
| Change in oxygen saturation | Before, during and 5 minutes after the end of the exercise and control interventions | Assessment of the peripheral oxygen saturation using a pulse oximeter |
| Change in Blood pressure | Before and 30 and 50 minutes after the end of the exercise and control interventions | Assessment of the systolic and diastolic blood pressure using an automatic device |
| Change in flow mediated dilation | Before and 30 minutes after the end of the exercise and control interventions | Assessment of the flow mediated dilation using a doppler ultrasound |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in affective response | Before and every 5 minutes during exercise and control interventions | Assessment of affective response using a felling scale |
| Change in heart rate | Before and continuously during exercise and control interventions | Assessment of heart rate using a heart rate monitor |
Countries
Brazil
Contacts
Primary ContactRaphael Dias, PhD
Backup ContactMarilia Correia, PhD
Outcome results
None listed