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Predictors of Mortality Among Ventilator Associated Pneumonia Patients

Predictors of Mortality Among Ventilator Associated Pneumonia Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06246994
Enrollment
140
Registered
2024-02-07
Start date
2024-03-31
Completion date
2025-09-30
Last updated
2024-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Brief summary

In this context, this study aims to explore the risk factors for mortality from VAP in respiratory ICU.

Detailed description

Pneumonia is the most common infection treated within ICUs and carries significant mortality risk . Ventilator-associated pneumonia (VAP) is a specific form of nosocomial pneumonia occurring in patients greater than 48 hours after intubation and the initiation of mechanical ventilation . VAP is considered a leading cause of morbidity and mortality among intensive care unit infections. Despite various preventive measures, the incidence of VAP remains high . In studies, VAP-related mortality is 14-70% . It is contemplated that there are independent risk factors, increasing VAP-related mortality . However, the question of which factors are associated with early or late mortality in patients with VAP diagnosis, remains unanswered. Early identification and understanding of the etiology of VAP in the ICU is essential to prevent mortality and morbidity.

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

This study will enroll: 1. adult participants over 18 years old who had undergone mechanical ventilation for longer than 48 hours. 2. Only the first episode of VAP for each patient will be included.

Exclusion criteria

1. Patients who are less than 18 years old. 2. Pneumonia diagnosed before mechanical ventilation.

Design outcomes

Primary

MeasureTime frameDescription
Mortality rate at 28 days.28 daysEvaluation of number of dead patients from vap wihin 28 days of infection and
Percentage of risk factors of VAP mortality.28 daysSearch for risk factors for mortality of vap wihin 28 days of infection.

Contacts

Primary ContactMarwa Kilany, Assisst- lecture
docmero1693@gmail.com01064123545
Backup ContactSaher Mahmoud, lecture
farida62014@gmail.com01002866364

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026