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Severe Head Trauma: Coagulation and CT-Scan Aggravation.

Severe Head Trauma: Coagulation and CT-Scan Aggravation.

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06246500
Acronym
TCA-COAG
Enrollment
23
Registered
2024-02-07
Start date
2021-05-11
Completion date
2021-07-08
Last updated
2024-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head Trauma

Brief summary

Retrospective, multicenter cohort study describing the biological, radiological and clinical criteria of patients managed for isolated severe head trauma between January 2016 and December 2018.

Detailed description

The objective of the study is to describe the evolution of CTscan lesions in patients with isolated Head Trauma between admission and re-evaluation after 24 hours.

Interventions

OTHERNo intervention

No intervention

Sponsors

Centre Hospitalier Annecy Genevois
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults * Patients informed and did not object to the collection of their medical data for the study * Patient admitted in Trauma center between January 2016 and December 2018 severe head injury defined by a Glasgow Coma Scale (GCS) \< 9 AND/OR Abnormalities on the first brain CT-scan with pathological transcranial Doppler (Vd \< 25 cm/s and IP \> 1.25)

Exclusion criteria

* Abbreviated Injury Score (AIS) head and neck ≤ 3 AND/OR AIS out of head and neck \> 3 * Taking drugs that interfere with hemostasis, such as anticoagulant or antiplatelet antiaggregants in preventive or curative doses; * Patients under guardianship * Patients still alive at the time of data collection AND opposed to the collection of their data

Design outcomes

Primary

MeasureTime frameDescription
Describe the evolution of CT scan lesions between admission and reassessment CT scan24 hoursNumber of patient with an aggravation of lesions on CT scan

Secondary

MeasureTime frameDescription
Causes of deathDay 28Causes of death
Describe the coagulation status on admission with severe head trauma trauma24 hoursFibrinogen level values
MortalityDay 28Mortality rate

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026