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Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in Lesotho

Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in Lesotho

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06246058
Enrollment
475
Registered
2024-02-07
Start date
2024-02-15
Completion date
2024-09-13
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Consumer Behavior, Health Behavior, Health Care Seeking Behavior, Health Care Utilization, Motivation, Recruitment, Researcher-Subject Relations, Social Behavior

Keywords

Social support, Uncertainty, Low-resource setting, Ambiguity aversion, Behavioral economics, Research administration, Recruitment success

Brief summary

The primary research objective is to examine how uncertainty towards a new medical treatment changes in patients when a partner (can be any close other, i.e. romantic partner, family member, or a close friend) supports the new treatment choice and is willing to be involved in the patient's treatment. I hypothesize that when the patients know that their partner supports uptake of the new medical treatment and will physically accompany them to the visit, patients will (1) experience lower levels of uncertainty and (2) report a higher likelihood of participating in a new treatment in the future, as compared to patients who face the decision about the new treatment alone.

Detailed description

Host trial: Uncertainty survey experiment This study uses a survey experiment with a hypothetical scenario (vignette) to test the concept of uncertainty and the impact of partner involvement in a hypothetical new medical treatment in patients seeking healthcare in the Butha Buthe district hospital. Specifically, this host trial will be a single-blinded randomized survey experimental design. This means that there will be two versions of the vignette and participants will be randomly given only one version (1:1 allocation). The participants will not be made aware that there is a different version of the vignette but the researchers will be aware of which version the participant receives. The difference between the vignettes (called behavioral manipulation) is whether or not the partner endorses the hypothetical new medical treatment related to the patient's current illness. See the Study measures Section for the specific vignettes. Study Within a Trial (SWAT): Impact of the researcher's attire on recruitment rates Within the host trial, the nested study on researcher's attire will take place as a Study Within A Trial or SWAT. SWAT is an increasingly recognized method of research that aims to improve the research methodology within an existing trial. The SWAT on researcher attire will take place in the recruitment phase of the host experiment with day-based cluster randomization between white coat versus casual attire assignment. These attire assignments will be given along with the given week's recruitment assignments to the two Basotho research assistants who will work on the host trial. The nested study does not impact the procedures of the survey experiment. Researcher's attire during recruitment will remain the same throughout the survey delivery until the end of the participant's study visit.

Interventions

BEHAVIORALPartner support

The intervention group's survey vignette will include a component of partner support which serves as the key behavioral manipulation tested for this study's primary outcome.

BEHAVIORALFormal recruiter attire

The SWAT will separately test recruitment rates - as measured by rate of survey completion divided by total number of individuals approached - based on how the recruiters are dressed. FORMAL dress code of the recruiter is the intervention in this case, defined as clinical attire alluding to some clinical authority.

BEHAVIORALWithout Partner support

The intervention group's survey vignette will NOT include a component of partner support which serves as the key behavioral manipulation tested for this study's primary outcome.

BEHAVIORALCasual recruiter attire

The SWAT will separately test recruitment rates - as measured by rate of survey completion divided by total number of individuals approached - based on how the recruiters are dressed. CASUAL dress code of the recruiter is the intervention in this case.

Sponsors

SolidarMed
CollaboratorOTHER
University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adults over 18 years of age * Are comfortable reading and writing in Sesotho or English * Attending as a patient in Butha Buthe-area hospital or health center for a known clinical diagnosis or standard health screening related to one of these illness categories: * HIV * Other sexually-transmitted infection (i.e. gonorrhea, syphilis, hepatitis) * Breathing problem/ tuberculosis * Heart issues/ blood pressure * Diabetes/ sugar level * Bone/ muscle problem * Mental health * Memory/ thinking problem * Teeth/ mouth problem * Cancer * Maternal health (i.e. pregnancy, post-partum care)

Exclusion criteria

* Have participated in this study before * Visible intoxication and/or distress, as deemed by trained research assistant * Unable to make independent decisions; unable to complete informed consent * Warrants emergency medical care * Visiting the hospital for another person (i.e. their child, relative, partner)

Design outcomes

Primary

MeasureTime frameDescription
AA-Med score1 time measurement immediately after interventionAmbiguity aversion score difference between two survey groups; AA-Med contains 6 response items, each scored from 1 to 4 (1=disagree completely; 4=agree completely)

Secondary

MeasureTime frameDescription
Recruitment rate1 time measurement immediately after interventionRecruitment success rate (fully participated/ approached) difference between two recruitment attire groups

Countries

Lesotho

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026