Birth Weight, Feeding Disorder Neonatal, Preterm
Conditions
Keywords
Feeding protocol, Neonates, Preterm, Very low birthweight, NICU
Brief summary
The goal of this clinical trial is to compare modified feeding protocol and current feeding protocol on neonatal outcomes in preterm infants who born with weight less than 2kg. The main questions it aims to answer are: * Is Modified feeding protocol will decrease the duration of parenteral nutrition and length of hospital stay? * Is Modified feeding protocol feasible, efficient, and safe in preterm infants? Participants will undergo the modified feeding protocol since birth until discharge.
Detailed description
two group in this study Prospective group: intervention group will undergo the modified feeding protocol Retrospective group: intervention group will undergo the current feeding protocol Both group will have care as routine care to this kind of patients But the differ will be in feeding protocol as initiation rate, advancement rate, human milk fortification rate The outcomes of both group will be compeered to meet the study objectives
Interventions
OTHERModified feeding Protocol
Initiation of feeding (fixed): 10cc/kg Advancement based on birthweight (fixed): \<750g: 15cc/kg/d 750-999g: 20cc/kg/d 1000-1249g: 25cc/kg/d 1250-1499g: 25cc/kg/d 1500-1749g: 35cc/kg/d 1750-2000g: 35cc/kg/d Starting Human milk fortification when feed reach at 70cc/kg/d
Sponsors
Imam Abdulrahman Bin Faisal University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
ALL
Age
No minimum to 2 Months
Healthy volunteers
No
Inclusion criteria
* Birth weight (\<2000g) * Gestational Age (\<37 week)
Exclusion criteria
* Metabolic Disorders * Congenital Heart Diseases * Chronic Lung Disease * Congenital Anomalies (can related to feeding) * Moderate to severe GERD * Necrotizing enterocolitis stage 3 (surgical) * Gastrointestinal surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Length of Stay (LOS) | Up to 8 weeks | Number of days that participant stayed at hospital |
| Duration of Total Parenteral Nutrition (TPN) | up to 2 weeks | Number of days that participant received Total Parenteral Nutrition (TPN) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of Necrotizing Enterocolitis | Up to 8 weeks | Stage 2, Stage 3 |
| Incidence of Feeding intolerance | Up to 8 weeks | abdominal grith more than 2 cm, gastric residual 50% of the last feed. |
Countries
Saudi Arabia
Outcome results
None listed