Serum and Urine Metabolome Studies in Patients With Acute Kidney Injury After Cardiac Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06245720

Enrollment

200

Registered

2024-02-07

Start date

2024-01-01

Completion date

2025-12-31

Last updated

2024-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery Associated Acute Kidney Injury

Brief summary

The goal of this observational study is to learn about serum and urine metabolome in patients after cardiac surgery.

Detailed description

The main objective of this study is to collect blood and urine samples from patients after cardiac surgery, and to perform metabolomic analysis to find the differential metabolites and their enrichment pathways in AKI patients and non-AKI patients.The secondary objective is to intervene in its enrichment pathway to find ways to improve CSA-AKI.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

1. Age\> 18 years old; 2. after cardiopulmonary bypass;

Exclusion criteria

1. Under the age of 18; 2. Previous chronic kidney disease or receiving renal replacement therapy; 3. Have a history of kidney transplantation or nephrectomy.

Design outcomes

Primary

Measure	Time frame	Description
serum and urine metabolome studies	January 2025 - December 2025	The preoperative and postoperative metabolomic differences in blood and urine between AKI group and non-AKI group were compared.

Countries

China

Outcome results