Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06243588

Enrollment

400

Registered

2024-02-06

Start date

2024-01-25

Completion date

2025-12-31

Last updated

2025-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ewing Sarcoma

Brief summary

assess whether there is a correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma. Identification of reliable prognostic factors could help to identify high-risk patients, which may require a different treatment and follow up.

Interventions

OTHERclinical records review

review the medical records, radiological imaging, and histological data of these patients

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Years to No maximum

Healthy volunteers

Inclusion criteria

* Male and female patients treated at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2021 * Age ≥ 2 years * Diagnosis of Ewing Sarcoma * Patients with available clinical and imaging data

Exclusion criteria

* At least one inclusion criterion not met

Design outcomes

Primary

Measure	Time frame	Description
Correlation	At baseline (Day 0)	Correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma.

Countries

Italy

Contacts

Primary ContactCostantino Errani

costantino.errani@ior.it0516366

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026