PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6

Perioperative Percutaneous Electrical Nerve Stimulation Via a Wearable Equipment on Postoperative Nausea and Vomiting（PONV） in Patients Undergoing Laparoscopy Abdominal Surgery: a Prospective Randomized Controlled Trial

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06241547

Enrollment

326

Registered

2024-02-05

Start date

2024-02-05

Completion date

2026-05-13

Last updated

2026-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Brief summary

This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.

Detailed description

Introduction: This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting. Method and analysis: A total of approximately 302 patients undergoing elective laparoscopic surgery will be enrolled. Participants will be randomly assigned to either a electrical stimulation group or a placebo group, with computer-generated randomization and concealed allocation using sealed envelopes. The electrical stimulation group will receive PC point electrical stimulation 30 minutes before surgery until 24 hours postoperatively, while the placebo group will wear a wristband without stimulation. The primary outcome will be the incidence of postoperative nausea and vomiting, with secondary outcomes including the incidence of nausea and vomiting within 24 hours after surgery, gastrointestinal and hemodynamic indices, postoperative recovery, hospital stay and cost, and complications.

Interventions

DEVICEelectrical stimualtion via EmeTerm bracelet

We planned to exert electrical stimulation via the bracelet.

DRUGantimetic drugs（ dexamethasone，ondansetron）

Antimetic drugs (dexamethasone ondansetron) are used to prevent postoperative nausea and vomiting.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients aged 18-65 years; 2. Patients undergoing elective laparoscopic surgery; 3. American Society of Anaesthesiologists(ASA) Grade 1 to 3; 4. Anesthesia: General Anesthesia, Tracheal Intubation; 5. BMI: ≥18, \<28; 6. Gender: female 7. Patients or their family members are able to comprehend the study protocol and are willing to participate in this research by providing written informed consent.

Exclusion criteria

1. There are incisions or scars in the wearing position of the device; 2. There is a local infection in the wearing position of the device; 3. upper extremity nerve injury; 4. history of spinal cord surgery; 5. Participated in other clinical trials within 4 weeks; 6. suffering from severe central nervous system disease or mental disorder; 7. Patients need to return to the ICU after surgery.

Design outcomes

Primary

Measure	Time frame	Description
Incidence of postoperative nausea and vomiting(PONV)	24 hours after surgery	Ask patients if they experienced nausea or vomiting 24 hours after surgery.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 18, 2026