Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06241079

Enrollment

582

Registered

2024-02-05

Start date

2003-03-31

Completion date

2023-02-01

Last updated

2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Squamous Cell Carcinoma

Brief summary

The goal of this multicenter retrospective cohort study is to evaluate the impact of different pathological regression types on survival and recurrence patterns, with a particular focus on ypT0N+ patients in patients with esophageal squamous cell carcinoma. The main questions it aims to answer are the survival and recurrence patterns among the different pathological regression types in patients with esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy.

Interventions

OTHERnon-intervention

non-intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* histologically confirmed potentially resectable ESCC, clinical stage T1-4N0-1M0 (stage I-III) according to the American Joint Committee on Cancer 6th edition staging criteria.

Exclusion criteria

* incomplete surgical resection, two-dimensional radiotherapy, and incomplete clinical data.

Design outcomes

Primary

Measure	Time frame	Description
Overall survival	From date of surgery until the date of death from any cause or last follow-up, assessed up to 10 years.	the time from the date of surgery to death or last follow-up (2023.01.31)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026