Obstructive Sleep Apnea
Conditions
Keywords
Obstructive Sleep Apnea, Nocturia, Lower urinary tract symptoms, Voiding diary, Nocturnal polyuria
Brief summary
The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.
Detailed description
The observation study will be performed on patients diagnosed with obstructive sleep apnoea. Patients will undergo routine examination for sleep apnoea and will be asked to fill in voiding diaries for 48 hours. The main goal of the study is to find whether there are any parameters of sleep apnoea associated with occurrence of the nocturia.
Interventions
OTHERVoiding diary
The patients with diagnosed OSA will be asked to fill in the voiding diary.
Sponsors
University Hospital Ostrava
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients diagnosed obstructive sleep apnoea (OSA ) * Apnea-Hypopnea Index (AHI) \> 15 * ability to fill in the voiding diaries * signed informed consent
Exclusion criteria
* patients using diuretics * patients with malignancies * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the parameters of sleep apnoea - (apnea-hypopnea index - AHI) | 3 months | The change in parameters of sleep apnoea - apnea-hypopnea index (AHI) will be monitored from the baseline to the end of follow-up, before and after the treatment intervention for correction of obstructive sleep apnoea (OSA). The obtained data will be correlated with the information from the voiding diary. The apnea-hypopnea index (AHI) is the combined average number of apneas and hypopneas that occur per hour of sleep. According to the American Academy of Sleep Medicine (AASM) it is categorized into mild (5-15 events/hour), moderate (15-30 events/hour), and severe (\> 30 events/hour).ollow-up, before and after the treatment intervention for correction of obstructive sleep apnoea (OSA). The obtained data will be correlated with the information from the voiding diary. |
| Change in the parameters of sleep apnoea - oxygen desaturation index (ODI) | 3 months | The change in parameters of sleep apnoea - oxygen desaturation index (ODI) will be monitored from the baseline to the end of follow-up, before and after the treatment intervention for correction of obstructive sleep apnoea (OSA). The obtained data will be correlated with the information from the voiding diary. ODI refers to the average number of desaturation episodes occurring per hour, where desaturation episodes are defined as a decrease in the mean oxygen saturation of ≥3% (over the last 120 seconds) that lasts for at least 10 seconds. |
| Change in the parameters of sleep apnoea - time under 90% saturation (T90) | 3 months | The change in parameters of sleep apnoea - time under 90% saturation (T90) will be monitored from the baseline to the end of follow-up, before and after the treatment intervention for correction of obstructive sleep apnoea (OSA). The obtained data will be correlated with the information from the voiding diary. T90 was defined as the proportion of cumulative sleep time with oxygen saturation below 90% in total sleep time. T90≤5% of the total sleep time was classified as light hypoxia, T90 of 5-10% as mild hypoxia,10-25% as moderate hypoxia, and \>25% as severe hypoxia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in the data from the voiding diary - functional capacity of the bladder | 3 months | The change in bladder-derived parameters will be monitored from the baseline to the end of follow-up - functional capacity of the bladder will be measured in milliliters (mL). |
| Change in the data from the voiding diary - daily diuresis | 3 months | The change in bladder-derived parameters will be monitored from the baseline to the end of follow-up - daily diuresis will be measured in milliliters (mL). |
| Change in the data from the voiding diary - number of voiding episodes | 3 months | The change in bladder-derived parameters will be monitored from the baseline to the end of follow-up - the number of voiding episodes during sleep will be counted and monitored. |
Countries
Czechia
Contacts
Primary ContactJiří Hynčica
Outcome results
None listed