Hypotension
Conditions
Keywords
TAPSE, PASP, HYPOTENSİON, PULMONER RESECTİON
Brief summary
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection. This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
Detailed description
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection. This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population. Patients will be measured by transthoracic echocardiography in the preoperative period, 15-30 minutes before induction. Basal hemodynamic parameters and non-invasive and/or hemodynamic values will be recorded every two minutes after induction until surgical incision.Patients with a 30% decrease in SBP from the baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension. Patients will be divided into 2 groups: 'with' and 'without' hypotension.
Interventions
OTHERhypotension
MAP below 55 mmHg or long-term (2 minutes or more) hypotensive attacks will be treated with ephedrine 0.1mg/kg.
Sponsors
Aydin Adnan Menderes University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Written informed consent; 2. 18-75 years old 3. ASA Physical Status 1-3; 4. Patients planned for pulmonary resection surgery
Exclusion criteria
1. The patient is pregnant 2. After cardiac surgery 3. Severe pulmonary hypertension 4. Severe valve disease 5. Hypertrophic or dilated cardiomyopathy 6. Presence of acute myocardial infarction 7. Patients with severe visual or hearing impairment/disability 8. ASA physical status IV or V 9. Ischemic heart disease, conduction disorder. 10. History of long-term use of certain medications (β-blockers, angiotensin converting enzyme inhibitors, analgesics, sedatives or tricyclic antidepressants)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| echocardiography | 30 minute | TAPSE/ PASP (mm/mmHg) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| tension | 4-5 hours | Intraoperative systolic arterial tension, diastolic arterial tension and mean arterial tension will be taken and recorded for the patients. |
Countries
Turkey (Türkiye)
Outcome results
None listed