Skip to content

A Multicenter External Validation of a Novel Prediction Model for Elbow Flexion Recovery After Nerve Transfer Surgery in Brachial Plexus Injuries

A Multicenter External Validation of a Novel Prediction Model for Elbow Flexion Recovery After Nerve Transfer Surgery in Brachial Plexus Injuries

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06237270
Enrollment
200
Registered
2024-02-01
Start date
2023-03-18
Completion date
2024-05-01
Last updated
2025-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brachial Plexus Injury

Keywords

nerve transfer, neurotization, brachial plexus injury, predictive factors, external validation, risk prediction model

Brief summary

The goal of this observational study is to validate a risk prediction model developed for unsuccessful elbow flexion recovery after nerve transfer surgery in patients with brachial plexus injury. The main question it aims to answer is how well a risk prediction model perform in a different dataset, which are patients with brachial plexus injury who underwent surgery in a different time period or a different hospital.

Interventions

PROCEDURENerve transfer surgery for elbow flexion

A functioning but less important nerve (e.g. spinal accessory nerve, phrenic nerve, fascicle of median nerve, or fascicle of ulnar nerve) was transferred to nerves innervating biceps or brachialis muscle to restore elbow flexion.

Sponsors

Lerdsin General Hospital
CollaboratorOTHER
Siriraj Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
10 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Traumatic brachial plexus injury patients underwent nerve transfer operation for re-innervation of elbow flexion at Siriraj Hospital between 2018 and 2020 and Lerdsin General Hospital between 2008 and 2022 * Patients had follow-up duration at least 24 months after surgery

Exclusion criteria

* Incomplete medical records * Patients underwent free functioning muscle transfer as primary surgery for elbow flexion * Obstetric brachial plexus injury * Radiation-induced brachial plexopathy

Design outcomes

Primary

MeasureTime frameDescription
Number of participants with failure of biceps recovery at 24 months24 monthsMedical research council motor grading system of less than 3 at 24 months after surgery

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026