Retrospective Data Analysis of CKRT (Continuous Kidney Replacement Therapy) Treatments in Adult Mode With multiFiltratePRO

Retrospective Data Analysis of CKRT Treatments in Adult Mode With multiFiltratePRO

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06236984

Acronym

CKRT-AKI

Enrollment

Registered

2024-02-01

Start date

2024-05-01

Completion date

2025-02-21

Last updated

2025-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, Renal Failure

Keywords

Continuous kidney replacement therapy

Brief summary

The multiFiltratePRO is a device for extracorporeal blood purification treatments. In this retrospective analysis, the treatments of patients who received at least one treatment with the investigational device as mentioned between January 2015 and January 2024 will be documented in a chronological order. No further control treatments will be investigated in this one-arm design. The design is considered to be appropriate to reflect daily clinical practice and to contribute to empirical evidence of performance of the multiFiltratePRO system.

Interventions

OTHERmultiFiltratePRO with all CKRT treatment modes

Retrospective Data Analysis of CKRT treatments in adult mode with multiFiltratePRO

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients with an indication for the extracorporeal blood treatment suffering from AKI who received CKRT adult mode treatment for at least once with: Heparin-Continuous veno-venous hemofiltration Hep-CVVH (Pre CVVH, Post CVVH and Pre-Post CVVH), Heparin-Continuous veno-venous hemodialysis Hep-CVVHD, Heparin-Continuous veno-venous hemodiafiltration Hep-CVVHDF (Pre-CVVHDF and Post-CVVHDF), Citrate-Calcium(Ci-Ca)-CVVHD, Citrate-Calcium(Ci-Ca) CVVHDF, between January 2015 and January 2024, with the investigational device, have to be included in the study in chronological order. * No age restriction for heparin modes * Age ≥ 18 years for Ci-Ca modes at treatment start * Patient´s body weight ≥ 40kg irrespective of age * Acute Kidney Injury (AKI) OR chronic dialysis patients with clinical indication for CKRT

Exclusion criteria

* Participation in an interventional clinical study during the retrospectively collected CKRT treatment data * Previous participation in the same study * No study-specific

Design outcomes

Primary

Measure	Time frame	Description
Analysis of treatments with multiFiltratePRO	documentation of max.7 treatment days	Performance data of defined multiFiltratePRO CKRT treatments in adult mode with regard to fluid balance (effluent dose) are analysed

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026