HUTT to Assess Cardiac Autonomic Nervous Function

Composite Autonomic Scoring Scale and HUTT to Assess Cardiac Autonomic Nervous Function: A Preliminary Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06236945

Enrollment

1122

Registered

2024-02-01

Start date

2024-01-31

Completion date

2025-12-31

Last updated

2024-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autonomic Nervous System Diseases

Brief summary

Autonomic nervous system diseases can cause abnormalities in the circulatory system, leading to malignant arrhythmia and sudden cardiac death. Standardized, operable, and simplified diagnostic indicators are urgently needed to evaluate autonomic nervous function, particularly cardiac autonomic nervous function. The investigators use HUTT in order to provide data support for cardiac autonomic nervous system evaluation.

Detailed description

In this study, 169 samples with vertical tilt test and 24-h Holter ECG data from February 13, 2023 to October 31, 2023 were selected. The AC, DC, and 24-h HRV were compared with the CASS to identify the indicators with the strongest correlation with the CASS sympathetic and vagus nerve scores. The best index was selected, and the score intervals were delimited. The sensitivity and specificity of the defined vagal and sympathetic intervals were analyzed.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

12 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* Vertical tilt test and 24-hour holter electrocardiogram were performed at the same time * Receive treatment in our hospital.

Exclusion criteria

* Taking benzodiazepines or hypotensive drugs within 24 hours * Combined with mental illness, severe dementia, serious organ disease * Severe arrhythmia, deep breathing and poor coordination of Valsaval movements affected the interpretation of results.

Design outcomes

Primary

Measure	Time frame	Description
To find the indicators which are most correlated to the sympathetic and vagus nerves.	February 13, 2023 to December 31, 2025	The investigators use HUTT and CASS score to find some indicators which are most correlated to the sympathetic and vagus nerves,so that can give data support to the clinical treatments

Countries

China

Contacts

Primary ContactYan Ding, M.D.

dingding13001300@126.com18633889260

Outcome results