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Overdose Prevention Centers and Behavioral Health

Assessing the Impact of Overdose Prevention Centers as a Polysubstance Use and Behavioral Health Intervention in New York City

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06236087
Enrollment
500
Registered
2024-02-01
Start date
2026-09-01
Completion date
2027-09-30
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overdose

Brief summary

The aims of this study are: (Aim 1) Identify sources of heterogeneous impacts of opioid prevention center (OPC) use on non-fatal and fatal overdose risk among individuals with histories of polysubstance use (PSU); (Aim 2) Estimate the impact of OPC use on treated psychiatric events among clients with histories of PSU, and; (Aim 3) Assess the barriers and facilitators of integrating mental health services into existing syringe service and OPC delivery models.

Detailed description

Aims 1 and 2 of this study will use secondary data to identify sources of heterogeneous impacts of OPC use on fatal and nonfatal overdose risk (Aim 1) and estimate the impact of OPC use on treated psychiatric events among clients with histories of PSU (Aim 2). Aim 3 of this study will use qualitative interviews with harm reduction staff to assess barriers and facilitators of integrating mental health services into existing syringe service and OPC delivery models.

Interventions

None listed

Sponsors

NYU Langone Health
Lead SponsorOTHER
Centers for Disease Control and Prevention
CollaboratorFED

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

Aims 1 and 2: * are 18 years of age or older; * engaged in syringe service program and/or overdose prevention center services in New York City in the past 30 days before the date of enrollment; * are able to complete assessments in English or Spanish; * are competent to give written informed consent at the time of the interview; * are able to provide informed consent; * self-report use of illicit opioids (e.g., heroin, fentanyl), illicit stimulants (e.g., powder cocaine, crack, methamphetamine), counterfeit prescription pills (defined as prescription pills obtained through the illicit drug market) or any injection drug use in the past 30 days, and * are able to participate for at least 6 months following enrollment. Aim 3 * are 18 years of age or older; * are employed by a harm reduction program; * are able to complete assessments in English; and * are able to provide informed consent.

Exclusion criteria

• Individuals not meeting the criteria detailed above for the respective Aims will not be eligible for participation in this study.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of Fatal OverdoseUp to Month 12Incidence of fatal overdose will be derived from overdose mortality data from the NYC Office of the Chief Medical Examiner.
Incidence of Non-Fatal OverdoseUp to Month 12Incidence of nonfatal overdose will be assessed using hospitalization and emergency department data from the NYC Regional Health Information Exchange (RHIO) and Statewide Research and Planning Cooperative System (SPARCS).
Incidence of Psychiatric Services UtilizationUp to Month 12Psychiatric services utilization will be assessed from SPARCS, RHIO, and NYS Medicaid.

Countries

United States

Contacts

CONTACTBennett Allen, PhD, MPA
Bennett.Allen@nyulangone.org646-501-3708
PRINCIPAL_INVESTIGATORBennett Allen, PhD, MPA

NYU Langone Health

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026