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Risk Identification of Long-term Complications

Risk Identification of Long-term Complications in the Recover Patients With Severe COVID-19

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06235866
Enrollment
500
Registered
2024-02-01
Start date
2023-02-01
Completion date
2025-11-01
Last updated
2024-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe COVID-19

Keywords

COVID-19 Pneumonia, Long-term complications, Lung function

Brief summary

The investigators retrospectively analyze the clinical characteristics of severe COVID-19 in our hospital, and then establish a prediction model for long-term complications in patients with severe COVID-19, and strengthen follow-up to improve the prognosis of patients.

Detailed description

At present, there is a lack of prediction models for the long-term complications of severe COVID-19. Therefore, the investigators used the hospital big data platform to retrospectively analyze the clinical characteristics of severe COVID-19 in our hospital, and conducted cohort follow-up of the changes in lung function including FEV1, FVC,FEV1% and DLCO, etc and and high-resolution CT of patients after discharge. COX model and other statistical methods were used to establish a prediction model for long-term complications of severe COVID-19, and early identification and intervention, strengthen follow-up, and improve the prognosis of patients.

Interventions

OTHERPulmonary rehabilitation

According to the pulmonary rehabilitation guidelines, patients with severe COVID-19 were given regular rehabilitation treatment, including breathing exercises and physical rehabilitation exercises.

Sponsors

Wuhan Central Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

The patient met the diagnostic criteria for severe COVID-19

Exclusion criteria

* Pregnant women Patients who died of COVID-19 Patients younger than 18 years of age without pulmonary CT

Design outcomes

Primary

MeasureTime frameDescription
Lung function1 yearPulmonary function indicators improved gradually
Imaging of the lung1 yearThe residual lesions in the lung were gradually absorbed

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026