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Wrist Position Sense in Individuals With Multiple Sclerosis

Examining the Relationship Between Wrist Position Sense and Manual Dexterity in Individuals With Multiple Sclerosis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06232850
Enrollment
48
Registered
2024-01-31
Start date
2024-01-11
Completion date
2024-04-01
Last updated
2026-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis

Keywords

Multiple Sclerosis, Manual Dexterity, Position Sense

Brief summary

No study has been found examining the effect of wrist position sense on manual dexterity in individuals with multiple sclerosis.The purpose of this study is to examine the effect of wrist position sense on manual dexterity of the hand.

Detailed description

Multiple sclerosis is a chronic demyelinating disease of the central nervous system that occurs in young adults and usually progresses with attacks and remissions. As the disease progresses, symptoms such as fatigue, muscle weakness, loss of balance, loss of sensation, spasticity, visual disturbances and bladder dysfunction are observed. In addition to these symptoms, hand functions may be affected even in the early stages of the disease. Appropriate motor control and mobility skills are required to perform manual dexterity effectively. Joint stabilization and perception of the joint's position and movement in space are needed for motor control of hand functions. In this process, position sense signals contribute significantly to the target localization and performance of the hand. Position sense signals must be constantly updated for the coordination and integration of hand position during manual activities such as holding or grasping an object. This is possible with a healthy sense of position. Although it is known that position sense is affected in MS patients, no study has been found examining the effect of wrist position sense on manual dexterity. The purpose of this study is to examine the effect of wrist position sense on hand dexterity. Patients' manual dexterity will be evaluated using the Purdue Pegboard Test, and wrist position sense will be evaluated using the K-FORCE Sens® electrogoniometer.

Interventions

OTHERPosition sense and manual dexterity evaluate

Position sense and manual dexterity evaluate

Sponsors

Pamukkale University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Patient group: * Disability score (EDSS: Expanded Disability Status Scale) should be between 0-3. * Being between the ages of 18-50 * Not having had an attack in the last 3 months * Scoring 24 points or above on the Mini-Mental State Examination * Patients diagnosed with relapsing-remitting MS with a disease duration of at least 2 years * Patients without spasticity according to MAS Control group: * Volunteers in a similar age range who agreed to participate in the study * Being between the ages of 18-50

Exclusion criteria

* Patient group: * Presence of diagnosed visual impairment * Having other chronic diseases not related to MS * Having any orthopedic, neurological, rheumatological or metabolic diagnosis that causes upper extremity involvement * History of hand and upper extremity disorders, peripheral nerve disorders, and medical or psychiatric disorders that may significantly affect cognitive function * Presence of wrist joint range of motion limitation Control group: * Having any orthopedic, neurological, rheumatological or metabolic diagnosis that causes upper extremity involvement * History of hand and upper extremity disorders, peripheral nerve disorders, and medical or psychiatric disorders that may significantly affect cognitive function * Presence of wrist joint range of motion limitation

Design outcomes

Primary

MeasureTime frameDescription
Wrist Position Sense Assessmentfour mounthWrist position sense will be assessed with the KFORCE Sens® electrogoniometer. Target measurement values of 30° for wrist flexion, 30° for extension, 10° for radial deviation and 15° for ulnar deviation will be used.

Secondary

MeasureTime frameDescription
Purdue Pegboard Test (PPT)four mounthPPT evaluates the gross motor skills of the arm, hand and fingers, as well as the fine motor skills of the fingers and fingertips, both unilaterally and bilaterally. It consists of pins, washers, nuts and assembly tests. The test consists of 5 sub-steps (inserting pins with the dominant/non-dominant hand/both hands, mathematical summation and assembly). The scoring of the test is the total number of pins, washers and nuts installed at the end of the given period. One trial will be made for each subtest.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORMüge İçelli Güneş, M.Sc.

Pamukkale University Denizli Health Services Vocational School of Higher Education

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 7, 2026