Extraction of the Compromised First Permanent Molars

The Extraction of Compromised First Permanent Molars in a Group of Egyptian Children

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06231823

Acronym

FPM

Enrollment

Registered

2024-01-30

Start date

2024-01-01

Completion date

2026-03-31

Last updated

2025-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries, Caries,Dental

Keywords

first permanent molar, molar incisor hypo mineralization, dental extraction, space closure

Brief summary

Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which leads to their inevitable extraction and implant placement. Extraction of compromised first permanent molars in 8-10-year-old children allows the mesial migration of the second permanent molars during their eruption, thereby favoring spontaneous space closure as a permanent solution.

Detailed description

Extraction of compromised first permanent molars in children decreases the burden of repeated restorative procedures for theses molars, which will eventually need frequent repair. This will end in their inevitable extraction with its consequences. The extraction of the FPM will be delivered by Nour Wahba, Dina Darwish, and Basma Nagi, lecturers in Pediatric Dentistry and Dental Public Health Department, faculty of Dentistry, Ain Shams University.All patients will be recalled for follow-up yearly for three-years. The first follow-up will be done after 6months to perform the Quality of life questionnaires. The position of the second permanent molar will be checked clinically and radiographically to evaluate the space between second premolar and the second molar.

Interventions

OTHERExtraction

Simple / surgical dental extraction for necrotic. irreversible pulpitis, unrestorable, and first permanent molars with sever molar incisor hypomineralization.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

8 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy patients' class I according to the American Society of Anesthesiologists (ASA class I) * Age: 8-10 years * Angle class I occlusion * The radiographic presence of the second premolar * The radiographic stages of development E or F for formation the second permanent molar. * First permanent molar that is severely affected by MIH, signs of necrosis, signs of irreversible pulpitis or non-restorability.

Exclusion criteria

* Refusal of the parents to sign the informed consent. * Signs of reversible pulpitis of first permanent molar. * Patients with severe malocclusion.

Design outcomes

Primary

Measure	Time frame	Description
clinical spontaneous space closure	3 years	Clinically, using periodontal probe measure the amount of space between the distal surface of second premolar and mesial surface of second permanent molar.
radiographic spontaneous space closure	3 years	radiographically, using panoramic radiograph

Secondary

Measure	Time frame	Description
assessment of the Quality of life	6 months	Measure the quality of life of the children before extraction and at 6 months follow-up using parent perception questionnaire and family impact scale (P-CPQ and FIS) and child perception questionnaire 8- 10 or 11-14 (CPQ 8-10; CPQ 11-14) according to the child's age.
Midline shift	3 years	Investigate the midline shift by clinical examination.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026