Testicular Cancer
Conditions
Brief summary
The aim of study is to differentiate between testicular tumors by their elastographic criteria (Stiffness \[hard to soft\] , Shape under compression , etc.) using ultrasound elastography techniques (shear wave/strain elastography) on suspected testicle that showed specific lesion on normal ultrasound examination.
Detailed description
Technique: Using a linear ultrasound probe supporting elastography techniques, either : Strain Elastography (SE) SE measures tissue stiffness by applying external tissue pressure \[3\]. Tissue dimensions change due to the applied pressure; this deformation is termed strain. Stiffer lesions deform less, and have correspondingly lower strain and higher Young's modulus. In strain imaging, tissue displacement is calculated by processing radiofrequency (RF) datasets obtained before and after compression \[4\]. Translucent colored elastograms (strain images) can be superimposed on B-mode images to provide complementary anatomic information. It is common to display the strain map as colored pixels on a red/blue scale or gray scale \[5\]. Or Shear wave elastography (SWE) Shear wave elastography differs from strain elastography, as it is a quantitative method of assessing tissue elasticity by measuring the speed of acoustic radiation force impulse-induced shear waves traveling in the tissue of interest. The compressive acoustic waves used for conventional B-mode image generation travel at high speeds through soft tissue (1450-1550 m/s). By contrast, mechanical shear waves used for shear wave elastography travel relatively slowly (1-10 m/s). Shear wave propagation velocity depends on tissue stiffness \[2, 4\]. Data collection: Data will be recorded as excel spreadsheet and statistical analysis using SPSS software version 22 Computer software: SPSS version 22 statistical software. Statistical tests: T-test.
Interventions
examining patient's testis with ultrasound elastography technique and collect data and results
Sponsors
Study design
Eligibility
Inclusion criteria
* i. Age : (15-65 years). * ii. Patient with history of testicular pain or discomfort or even without clinical symptoms. * iii. Patient with any predisposing factors as mentioned before in the background. * iv. Patient with history of cancer of other organs (not testicular tumors).
Exclusion criteria
* i. patient refused to be included in the study. ii. infarct correlation with patient history and symptoms is important. iii. Infections as focal orchitis. iv. History of trauma (hematoma exclusion).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| collect data of our elastography examination and acknowledge more information about certain testicular tumors and percentage of malignant and bengin tumors of our specimen using ultrasound machine shear wave mode | baseline | differentiate between certain types of testicular tumors according to their elastography criteria using ultrasound machine shear wave mode according to the elasticity of tumor tissue |