Body Massage Oil From Snake Fruit, Facial Mask From Snake Fruit, Jelly From Snake Fruit
Conditions
Brief summary
This study consisted of three sub-studies including 1) development and evaluation of body massage oil from Snake fruit on skin moisture, elasticity, oiliness, and melanin in healthy participants 2) development and evaluation of facial mask from Snake fruit on skin moisture, elasticity, oiliness, and melanin in healthy participants and 3) development and evaluation of ready-to-drink jelly from Snake fruit on controlling blood glucose and endurance time in healthy participants.
Detailed description
Study 1: senventy-one male and female participants, aged 23.99 ± 5.68 years were randomly assigned into 3 groups including 1) control group (n = 23): participants received Thai massage without any oil for 1 hour/day, 1 day/week for 12 weeks 2) treatment-1 group (n = 23): participants received Thai massage with pure coconut oil which is a popular oil used in spa for 1 hour/day, 1 day/week for 12 weeks and 3) treatment-2 group (n = 25): participants received Thai massage with oil mixed with Snake fruit extract for 1 hour/day, 1 day/week for 12 weeks. Study 2: fifty-nine male and female participants, aged 23.39 ± 4.84 years were randomly assigned into 2 groups including 1) control group (n = 29): participants did not receive any facial mask for 12 weeks and 2) treatment group (n = 30): participants received home-based program facial mask with Snake fruit extract for 30 min/day, 2 days/week for 12 weeks. Study 3: this study was divided into 2 sub-stidies. Study 3.1: twenty-five male and female participants, aged 22.60 ± 3.33 years were randomly consumed with either control jelly or jelly with Snake fruit juice at 3.5 g/kg body weight. All participants were analyzed for blood glucose level before consumption and after consumption at 30, 60, 90, and 120 min. Study 3.2: twenty-three male and female participants, aged 21.57 ± 1.88 years were randomly consumed with either control jelly or jelly with Snake fruit juice at 3.5 g/kg body weight. After each consumption, all participants performed leg cycling at intensity 60% of maximal oxygen consumption as long as tolerance (time to exhaustion test).
Interventions
OTHERThai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Interventions among the 3 studies were categorized as other.
Sponsors
Burapha University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)
Intervention model description
Study 1 and 2 were parallel model, study 3 was crossover model.
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Man or woman * Aged between 18 to 35 years * Healthy * Interested in body massage with oil or facial mask or jelly from Snake fruit
Exclusion criteria
* History of adverse effects from body massage * Skin allergy * Skin disorders * Skin wounds * History of allergy to coconut or plant oil * History of allergy to facial mask, i.e., mask from fruit * History of allergy to Snake fruit or gelatin * Signs or symptoms of fever or infection * Abnormal body mass index * Regular smokers or alcohol drinkers (\>2 times per week) * Regular exerciser (\>2 times per week or \>150 min per week) * Regular intake of dietary supplements, i.e., vitamins, antioxidants * Hypertension, diabetes, cardiovascular disease, respiratory disease, endocrine disease, neuromuscular disease, musculoskeletal disease, liver disease, renal disease, immune disease, infectious disease, or cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Level of skin moisture | Before intervention, immediately after intervention, ends of week 4, week 8, and week 12 | Study 1 and 2 determined level of skin moisture in arbitrary unit (no unit) using Multiprobe Adapter System with Corneometer® CM 825 probe |
| Level of skin elasticity | Before intervention, immediately after intervention, ends of week 4, week 8, and week 12 | Study 1 and 2 determined level of skin elasticity in arbitrary unit (no unit) using Multiprobe Adapter System with Cutometer® 580 probe |
| Level of skin oiliness | Before intervention, immediately after intervention, ends of week 4, week 8, and week 12 | Study 1 and 2 determined level of skin oiliness in arbitrary unit (no unit) using Multiprobe Adapter System with Sebumeter® SM 815 probe |
| Level of skin melanin | Before intervention, immediately after intervention, ends of week 4, week 8, and week 12 | Study 1 and 2 determined level of skin melanin in arbitrary unit (no unit) using Multiprobe Adapter System with Mexameter® MX18 probe |
| Level of blood glucose | Before jelly consumption and after jelly consumption at 30, 60, 90, and 120 minutes | Study 3.1 determined level of blood glucose in mg/dL unit |
| Endurance time | After jelly consumption for 30 minutes | Study 3.2 determined endurance time by cycling at 60% of maximum oxygen consumption as long as possible (time to exhaustion test) |
| Concentration of interferon-gamma | Before and immediately after endurance time test | Study 3.2 determined concentration of interferon-gamma in serum in pg (picogram)/mL unit |
| Concentration of tumor necrosis factor-alpha | Before and immediately after endurance time test | Study 3.2 determined concentration of tumor necrosis factor-alpha in serum in pg (picogram)/mL unit |
Countries
Thailand
Outcome results
None listed