Role of Ultrasound Guided Transversus Abdominis Plane Block in Pain Control After Hepatectomy

Ultrasound Guided Oblique Subcostal Transversus Abdominis Plane Block(TAP) Versus Both Subcostal and Posterior TAP Block as Postoperative Analgesia in Hepatectomy

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06224179

Acronym

U/STAP

Enrollment

Registered

2024-01-25

Start date

2024-02-01

Completion date

2024-06-01

Last updated

2024-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia

Brief summary

Inadequately managed acute pain following abdominal surgery originates from somatic pain signals in the abdominal wall and is linked to various unfavorable postoperative outcomes. These consequences encompass patient distress, respiratory complications, delirium, myocardial ischemia, extended hospital stays, an elevated risk of chronic pain, heightened analgesic consumption, delayed bowel function, and an increased need for rescue analgesics. This study aims to assess the postoperative analgesic efficacy of ultrasound-guided Transversus Abdominis Plane (TAP) block using oblique subcostal and posterior approaches in hepatectomy.

Detailed description

Pain control is vital to achieve enhanced recovery after abdominal surgeries . TAP block had been demonstrated to improve pain related outcomes after abdominal surgeries. Postoperative pain management for patients undergoing hepatic resection is a challenge due to the risk of perioperative liver dysfunction.TAP block is a promising regional analgesic technique. This study aimed to evaluate the effect of US-guided subcostal approach versus combination of both subcostal and posterior approaches of TAP block The patients will be randomly divided into two groups : group A will recieve oblique subcostal TAP block and group B will recieve both subcostal and posterior TAP block .

Interventions

PROCEDUREultrasound guided subcostal TAP block

patients will be randomly divided into two groups using a computer generated random number chart. Group A received ultrasound guided subcostal TAP block,

PROCEDUREultrasound guided combined posterior and subcostal TAP block

patients will be randomly divided into two groups using a computer generated random number chart. Group B received ultrasound guided combined posterior and subcostal TAP block,

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.

Exclusion criteria

* patients under 18 years of age. * History of Allergic reactions to study drugs. * Opioid or analgesic abuse, and chronic treatment with opioids, or non-steroidal anti-inflammatory drugs. * History of bleeding tendency or coagulopathy .

Design outcomes

Primary

Measure	Time frame	Description
postoperative analgesia (VAS) during the 1st 24 hours in ICU	24 hours	Pain will be assessed on admission and at 2, 4, 8, 12 and 24 hours at rest and with passive flexion of hip and knee joint using visual analogue scale (VAS) ranging from 0 for no pain to 10 for worst pain.

Contacts

Primary ContactAhmed El-Dolah, lecturer of Anesthesia

a_wagih82@yahoo.com+20111113077

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026