A Registry Study of Biomarkers in Heart Valve Disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06223906

Acronym

BIOMS-HVD

Enrollment

200000

Registered

2024-01-25

Start date

2016-01-01

Completion date

2030-01-01

Last updated

2024-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases

Brief summary

Valvular Heart Disease, impacting 2.5% of the population, is predominantly observed in the elderly and is on the rise. The primary conditions within this category are Aortic Stenosis and Mitral Regurgitation. These conditions are linked to considerable morbidity and mortality, presenting a formidable challenge in optimizing treatment strategies. Pathophysiology of Valvular Heart Disease remains poorly known. The aim of the present study is to identify biomarkers involved in this disease using multi-omics approaches

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients clinically diagnosed with heart valve disease in Beijing Anzhen Hospital

Exclusion criteria

* Age \< 18 years * Failure to obtain medical records and ultrasound data * Refuse follow-up

Design outcomes

Primary

Measure	Time frame	Description
All-cause death	These data is collected during follow-up visit at 12 months after discharge	whether recidivation happened,whether other related disease happened

Secondary

Measure	Time frame	Description
HF rehospitalization	These data is collected during follow-up visit at 12 months after discharge	heart failure related hospitalization within 1 years of discharge

Countries

China

Contacts

Primary ContactYuan Wang, Dr

wangyuan980510@163.com13910161443

Backup ContactRui Lin, Dr

linrui2235@163.com15724230598

Outcome results